Evidence map›Paper›PMID 31677078›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2020

Pattern and interpretation of hepatitis B virus markers among pregnant women in North East Egypt.

Rania Kishk, Mohamed Mandour, Mohamed Elprince, Ayman Salem, Nader Nemr, Mohammed Eida, Mostafa Ragheb

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Rania KishkMicrobiology and Immunology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt. rankishk@yahoo.com.
Mohamed MandourClinical Pathology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Mohamed ElprinceObstetrics and Gynecology Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Ayman SalemInternal Medicine Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Nader NemrEndemic and Infectious Diseases Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Mohammed EidaEndemic and Infectious Diseases Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Mostafa RaghebEndemic and Infectious Diseases Department, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Suez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatitis B vaccination of newborns (HBV) and surveillance of pregnant women during antenatal care are complementary to prevent mother to child transmission (MTCT) of HBV infection.

aimThe aim was to identify the prevalence and pattern of HBV infection in pregnant women born before and after implementing HBV vaccination of newborn in Egypt.

methodsThe study included 600 women attended antenatal clinic of the Suez Canal University Hospital, Ismailia, Egypt. All were inquired about risk factors of HBV infection, vaccination, and screened for hepatitis markers. HBsAg carriers were tested for HBeAg, HBeAb, ALT, and HBV DNA. Participants were divided into group 1 of 285 (47.5%) vaccinated women ≤ 25 years, and 315 (52.5%) non-vaccinated > 25 years.

resultsThe prevalence of HBcAg, HBsAg, and HBsAb were 18.3%, 5.0%, and 30.7%. Of the 110 women exposed to infection, 40 (36.4%) cleared infection, 30 (27.2%) were HBsAg carriers, and 40 (36.4%) showed isolated HBcAb. HBsAg carriers were HBeAg negative, HBeAb positive, and HBV-DNA positive and had high ALT. Group 1 had significantly higher frequency of vaccination-related immunity, lower frequency of isolated HBcAb, and susceptibles than group 2 (44.9%, 3.5%, and 38.6% vs. 4.1%, 9.5%, and 75.9% ). The prevalence of HBV exposure and chronic HBsAb carriers in both groups were close (4.9% and 16.5% for group 1 vs. 5.1% and 20% for group 2, p > 0.05).

conclusionAlthough the outcomes of HBV infection were favorable in vaccinated group, chronic HBV represents a potential risk for MTCT that necessitates screening during pregnancy in all public health care settings.

Indexed as

AdultCarrier StateCross-Sectional StudiesDNA, ViralEgyptFemaleGenotypeHepatitis B AntibodiesHepatitis B, ChronicHepatitis B Surface AntigensHepatitis B VaccinesHepatitis B virusHumansInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousDNA, ViralHepatitis B AntibodiesHepatitis B Surface AntigensHepatitis B VaccinesEgyptHBVHepatitis markersPregnancyVaccination

Identifiers

PMID31677078
PMCPMC7203367
OpenAlexW2983738025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.