Evidence map›Paper›PMID 31676970›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

A conceptual map of health-related quality of life dimensions: key lessons for a new instrument.

Jan Abel Olsen, RoseAnne Misajon

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Measurement properties of the EQ-5D in populations with a mean age of ≥ 75 years: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Pooled it
  2. Dimensions Used in Instruments for QALY Calculation: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  3. Trial
  4. Article
  5. Empirical comparison of health-related quality of life and subjective well-being measures in Australian adolescents.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  6. Measuring Whole Person Health: A Scoping Review.Journal of integrative and complementary medicine · 2025
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  13. Quantifying health-related quality of life in Malaysian type 2 diabetes: focusing on complication types and severity.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
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  15. Extending the EQ-5D: the case for a complementary set of 4 psycho-social dimensions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jan Abel OlsenDepartment of Community Medicine, University of Tromsø - The Arctic University of Norway, Tromsø, 9037, Norway. jan.abel.olsen@uit.no.ORCID http://orcid.org/0000-0001-9472-2669
RoseAnne MisajonSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.

Funding

The Researche Council of Norway 221452
6 · The paper itself

Abstract

purposeQuality-adjusted life years (QALYs) represent a critical metric in economic evaluations impacting key healthcare decisions in many countries. However, there is widespread disagreement as to which is the best of the health state utility (HSU) instruments that are designed to measure the Q in the QALY. Instruments differ in their descriptive systems as well as their valuation methodologies; that is, they simply measure different things. We propose a visual framework that can be utilized to make meaningful comparisons across HSU instruments.

methodsThe framework expands on existing HRQoL models, by incorporating four distinctive continua, and by putting HRQoL within the broader notion of subjective well-being (SWB). Using this conceptual map, we locate the five most widely used HSU-instruments (EQ-5D, SF-6D, HUI, 15D, AQoL).

resultsBy individually mapping dimensions onto this visual framework, we provide a clear picture of the significant conceptual and operational differences between instruments. Moreover, the conceptual map demonstrates the varying extent to which each instrument moves outside the traditional biomedical focus of physical health, to also incorporate indicators of mental health and social well-being.

conclusionOur visual comparison provides useful insights to assess the suitability of different instruments for particular purposes. Following on from this comparative analyses, we extract some important lessons for a new instrument that cover the domains of physical, mental and social aspects of health, i.e. it is in alignment with the seminal 1948 WHO definition of health.

Indexed as

Quality-Adjusted Life YearsAdultAgedCost-Benefit AnalysisDecision MakingFemaleHealth StatusHumansMaleMental HealthMiddle AgedPsychometricsQuality of LifeSurveys and QuestionnairesEQ-5DHealth state utility instrumentsQALYsSF-6D

Identifiers

PMID31676970
PMCPMC7028807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.