Evidence map›Paper›PMID 31676963›Full record

ReviewCellular and molecular life sciences : CMLS2020

Roles of vitamins in stem cells.

Carlos Godoy-Parejo, Chunhao Deng, Yumeng Zhang, Weiwei Liu, Guokai Chen

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Review
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  9. Article
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  14. Article
  15. Metabolic regulation of somatic stem cells in vivo.Nature reviews. Molecular cell biology · 2022
    Review
  16. Article
  17. Role of vitamins in the metabolic syndrome and cardiovascular disease.Pflugers Archiv : European journal of physiology · 2022
    Review
  18. Article
  19. Review
  20. Regulation of energy metabolism in human pluripotent stem cells.Cellular and molecular life sciences : CMLS · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Carlos Godoy-ParejoCentre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Chunhao DengCentre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Yumeng ZhangCentre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Weiwei LiuCentre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Guokai ChenCentre of Reproduction, Development and Aging, Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China. guokaichen@um.edu.mo.ORCID http://orcid.org/0000-0003-0921-8244
University of Macau · MO

Funding

Fundo para o Desenvolvimento das Ciências e da Tecnologia FDCT/0059/2019/A1Fundo para o Desenvolvimento das Ciências e da Tecnologia FDCT/131/2014/A3, FDCT/056/2015/A2Universidade de Macau MYRG2018-00135-FHS
6 · The paper itself

Abstract

Stem cells can differentiate to diverse cell types in our body, and they hold great promises in both basic research and clinical therapies. For specific stem cell types, distinctive nutritional and signaling components are required to maintain the proliferation capacity and differentiation potential in cell culture. Various vitamins play essential roles in stem cell culture to modulate cell survival, proliferation and differentiation. Besides their common nutritional functions, specific vitamins are recently shown to modulate signal transduction and epigenetics. In this article, we will first review classical vitamin functions in both somatic and stem cell cultures. We will then focus on how stem cells could be modulated by vitamins beyond their nutritional roles. We believe that a better understanding of vitamin functions will significantly benefit stem cell research, and help realize their potentials in regenerative medicine.

Indexed as

Cell DifferentiationCell ProliferationRegenerative MedicineAnimalsEpigenesis, GeneticHumansSignal TransductionStem CellsVitaminsVitaminsCell cultureEmbryogenesisStem cellsVitaminVitamin AVitamin B3Vitamin CVitamin E

Identifiers

PMID31676963
PMCPMC11104807
OpenAlexW2987073278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.