ArticleInsights into imaging2019
Can imaging be the new yardstick for diagnosing peripheral neuropathy?-a comparison between high resolution ultrasound and MR neurography with an approach to diagnosis.
Article in Insights into imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 60 citations in OpenAlex.
- Review
- High-resolution ultrasound vs. MR neurography in upper extremity neuropathies: exploratory analysis of perceived additional diagnostic value in routine clinical practice.European radiology · 2026Observational
- "Small but mighty" - A radiologists' primer for ultrasound imaging of the smaller peripheral nerves.Skeletal radiology · 2025Review
- Quantitative Ultrashort Echo Time MRI for Evaluation of Sciatic Nerve Degeneration and Regeneration in Rat Models.Radiology · 2025Article
- Clinical Anatomy and Diagnostic Challenges in Peripheral Nerve Trauma for the Forensic Physician.Diagnostics (Basel, Switzerland) · 2025Review
- Peripheral nerve ultrasound: a survival guide for the practicing radiologist with updates.The ultrasound journal · 2025Review
- Diffusion tensor imaging in peroneal neuropathy: a prospective, single-centre study.BMJ neurology open · 2025Article
- Injury Patterns, Imaging Findings, and Prognosis for Muscle Strength Recovery in Surgical Infraclavicular Brachial Plexus Injuries.Journal of hand surgery global online · 2024Article
- Advances in Imaging of Compressive Neuropathies.Hand clinics · 2024Review
- Quantitative magnetic resonance neurography in chronic inflammatory demyelinating polyradiculoneuropathy: A longitudinal study over 6 years.Annals of clinical and translational neurology · 2024Article
- Diagnostic performance of deep learning-based reconstruction algorithm in 3D MR neurography.Skeletal radiology · 2023Article
- Peripheral nerve sheath tumour mimicking deep calf thrombus: An incidental finding during lower limb venous Doppler ultrasound.Ultrasound (Leeds, England) · 2023Article
- Future Considerations in the Diagnosis and Treatment of Compressive Neuropathies of the Upper Extremity.Journal of hand surgery global online · 2023Review
- Review
- Imaging diagnosis in peripheral nerve injury.Frontiers in neurology · 2023Review
- Neuropathy Score Reporting and Data System (NS-RADS): MRI Reporting Guideline of Peripheral Neuropathy Explained and Reviewed.Skeletal radiology · 2022Review
- Traumatic neuromas of peripheral nerves: Diagnosis, management and future perspectives.Frontiers in neurology · 2022Review
- Fully Convolutional Neural Network Deep Learning Model Fully in Patients with Type 2 Diabetes Complicated with Peripheral Neuropathy by High-Frequency Ultrasound Image.Computational and mathematical methods in medicine · 2022Article
- Imaging of traumatic peripheral nerve injuries.Journal of clinical orthopaedics and trauma · 2021Article
- Advances in imaging technologies for the assessment of peripheral neuropathies in rheumatoid arthritis.Rheumatology international · 2021Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePeripheral neuropathies are a group of disorders which affect the peripheral nervous system which have been conventionally diagnosed using electrodiagnostic studies. This study was carried out to assess the role of imaging in diagnosing peripheral mononeuropathy as exact anatomical localisation of the pathology is possible using high-resolution ultrasound and MR neurography, the modalities assessed in this study.
methodA hospital-based prospective analytical study was carried out in a resource-limited setting on 180 peripheral nerves in 131 patients with symptoms of peripheral mononeuropathy after taking IRB approval. Each patient underwent high-resolution ultrasound examination and MR neurography, findings of which were then compared and statistically analysed assuming electrodiagnostic findings as the gold standard.
resultsOverall, the diagnostic accuracy was highest for the proton density fat-saturated MR sequence (93.89%) followed by high-resolution ultrasound (80%). The sensitivity was highest for proton density fat-saturated sequence while the T1 MR sequence had the highest specificity. Combined diagnostic accuracy of both modalities was calculated to be 93.33% with a negative predictive value of 80%. High-resolution ultrasound and MRI equally detected the cases with nerve discontinuity, while neuromas were better identified on MRI.
conclusionWith the advent of higher frequency probes and improved MR field strength, imaging of peripheral nerves is possible with better accuracy. Imaging assessment of nerves allows anatomical delineation with identification of exact site of involvement. This comparative study demonstrates the role of imaging in diagnosing peripheral nerve pathologies with the accuracy of MRI as high as 93.89% which may serve as an imaging gold standard. High-resolution ultrasound, being quicker, cost effective and a comparable accuracy of 80% can serve as a reliable screening tool. This study incorporates a larger study group and compares HRUS with MRI, taking NCV as gold standard, which has not been done in the preceding studies. With this study, we conclude that these two imaging modalities are not mutually exclusive. Rather, they complement each other and can be used in conjunction as an imaging yardstick for diagnosing peripheral neuropathies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.