ArticleScientific reports2019
Tissue-specific expression profiles and positive selection analysis in the tree swallow (Tachycineta bicolor) using a de novo transcriptome assembly.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
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- Transcriptome-wide expression landscape and starch synthesis pathway co-expression network in sorghum.The plant genome · 2024Article
- Genomic Variation, Population History, and Long-Term Genetic Adaptation to High Altitudes in Tibetan Partridge (Perdix hodgsoniae).Molecular biology and evolution · 2023Article
- Genome assembly of the foot-flagging frog, Staurois parvus: a resource for understanding mechanisms of behavior.G3 (Bethesda, Md.) · 2023Article
- Rapid adaptation to a novel pathogen through disease tolerance in a wild songbird.PLoS pathogens · 2023Article
- A chromosome-scale genome assembly of the false clownfish, Amphiprion ocellaris.G3 (Bethesda, Md.) · 2022Article
- Mathematical model for the relationship between single-cell and bulk gene expression to clarify the interpretation of bulk gene expression data.Computational and structural biotechnology journal · 2022Article
- Computational Methods for Prediction of Human Protein-Phenotype Associations: A Review.Phenomics (Cham, Switzerland) · 2021Review
- Article
- Experimental competition induces immediate and lasting effects on the neurogenome in free-living female birds.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Design, challenges, and the potential of transcriptomics to understand social behavior.Current zoology · 2020Article
- Influence of heat stress on reference genes stability in heart and liver of two chickens genotypes.PloS one · 2020Article
- Transcriptome of the Southern MuriquiFrontiers in genetics · 2020Article
- The neurogenomic transition from territory establishment to parenting in a territorial female songbird.BMC genomics · 2019Article
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4 authors.
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Abstract
Tree swallows (Tachycineta bicolor) are one of the most commonly studied wild birds in North America. They have advanced numerous research areas, including life history, physiology, and organismal responses to global change; however, transcriptomic resources are scarce. To further advance the utility of this system for biologists across disciplines, we generated a transcriptome for the tree swallow using six tissues (brain, blood, ovary, spleen, liver, and muscle) collected from breeding females. We de novo assembled 207,739 transcripts, which we aligned to 14,717 high confidence protein-coding genes. We then characterized each tissue with regard to its unique genes and processes and applied this transcriptome to two fundamental questions in evolutionary biology and endocrinology. First, we analyzed 3,015 single-copy orthologs and identified 46 genes under positive selection in the tree swallow lineage, including those with putative links to adaptations in this species. Second, we analyzed tissue-specific expression patterns of genes involved in sex steroidogenesis and processing. Enzymes capable of synthesizing these behaviorally relevant hormones were largely limited to the ovary, whereas steroid binding genes were found in nearly all other tissues, highlighting the potential for local regulation of sex steroid-mediated traits. These analyses provide new insights into potential sources of phenotypic variation in a free-living female bird and advance our understanding of fundamental questions in evolutionary and organismal biology.
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