Evidence map›Paper›PMID 31676650›Full record

ArticleBMJ open2019

Effects of physical activity and sedentary behaviour on cardiometabolic risk factors and cognitive function in children: protocol for a cohort study.

Yajie Lv, Li Cai, Zhaohuan Gui, Xia Zeng, Minyi Tan, Nianqing Wan, Lijuan Lai, Shaomin Lu, Weiqing Tan, Yajun Chen

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03582709 (Prospective Cohort Study on Cognition and Cardiovascular Disease of Sedentary Behaviors in Children), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03582709 enrolling by invitationnot on this map

Prospective Cohort Study on Cognition and Cardiovascular Disease of Sedentary Behaviors in Children

TypeobservationalSponsorCHEN YajunRan2017 to 2026Enrolled1,000ConditionsSedentary Behavior, Cognition, Cardiovascular-related Disease
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Association between weekend catch-up sleep and executive functions in Chinese school-aged children.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yajie LvDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-9598-920X
Li CaiDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Zhaohuan GuiDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Xia ZengDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Minyi TanDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Nianqing WanDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Lijuan LaiDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Shaomin LuDepartment of Child Health, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Weiqing TanHealth Promotion Center for Primary and Secondary Schools of Guangzhou Municipality, Guangzhou, China.
Yajun ChenDepartment of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, China chenyj68@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough studies showed that physical activity (PA) and sedentary behaviour (SB) were associated with cardiometabolic risk factors and cognitive function, both independent and combined associations among them are inconsistent. Cardiometabolic risk factors are also associated with cognitive function, but research of children is limited. Additionally, the brain level mechanisms have not been fully established. The proposed study aims to explore the associations and mechanisms of PA and SB on cognitive function and cardiometabolic risk factors in children. METHODS AND ANALYSIS: This is a school-based prospective cohort study. A total of 8324 participants of this study are primary school students aged 7-12 years old who are followed up every 2 years from January 2017 to December 2026. We used a stratified cluster random sampling to select five primary schools in Guangzhou, China. There are three phases at baseline. At phase I, we collect PA, SB and cognitive function by questionnaires and also conduct anthropometric and biochemical measurements in all participants. At phase II, PA, SB and cognitive function are measured respectively by accelerometers and cognitive tasks among participants randomly selected from four subgroups with different SB and PA levels. At phase III, event-related potentials are recorded using electroencephalogram during a cognitive task among participants randomly selected from phase II. We plan to follow-up all participants until they graduate from high school. The process applied at baseline and follow-up are approximately identical. ETHICS AND DISSEMINATION: Procedures described in this manuscript have been approved by the Ethical Review Committee for Biomedical Research, School of Public Health, Sun Yat-sen University (L2016-010). All parents or guardians of participants signed the informed consent form voluntarily before participating in the study. The findings of the study will be published in peer-reviewed journals. TRIAL REGISTRATION NUMBER: NCT03582709.

Indexed as

CognitionExerciseSedentary BehaviorAccelerometryBlood GlucoseCardiovascular DiseasesChildCholesterolCohort StudiesDyslipidemiasElectroencephalographyEvoked PotentialsFemaleGlucose Metabolism DisordersHumansLipoproteins, HDLBlood GlucoseCholesterolLipoproteins, HDLLipoproteins, LDLTriglyceridescardio-metabolic risk factorschildrencognitive functionphysical activitysedentary behaviour

Identifiers

PMID31676650
PMCPMC6830669

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.