Evidence map›Paper›PMID 31676588›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2019

Targeting mTOR in Head and Neck Cancer-Response.

J Silvio Gutkind, Terry A Day, Scott M Lippman, Eva Szabo

Abstract readLetterComment
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

J Silvio GutkindUniversity of California San Diego (UCSD) Moores Cancer Center, San Diego, California. sgutkind@ucsd.edu.
Terry A DayMedical University of South Carolina, Charleston, South Carolina.
Scott M LippmanUniversity of California San Diego (UCSD) Moores Cancer Center, San Diego, California.
Eva SzaboNCI, Potomac, Maryland.

Funding

Targeting Signaling Vulnerabilities for Oral Cancer PreventionR01DE026644 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jorge Silvio Gutkind, SCOTT M LIPPMAN · 2017 to 2026
$4.7M
Signal Transduction by PI3K/mTORR01DE030497 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GUTKIND, JORGE SILVIO, ZHANG, JIN · 2021 to 2025
$2.4M
Targeting the EGFR-PI3K/mTOR Signaling Circuitry: A Network-Based Approach for Oral Cancer Precision TherapyR01DE026870 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GUTKIND, JORGE SILVIO · 2018 to 2022
$2.3M
NIDCR NIH HHS R01 DE026644NIDCR NIH HHS R01 DE026870NIDCR NIH HHS R01 DE030497
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Head and Neck NeoplasmsSirolimusHumansSignal TransductionTOR Serine-Threonine KinasesMTOR protein, humanSirolimusTOR Serine-Threonine Kinases

Identifiers

PMID31676588
PMCPMC10224677

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.