ReviewClinical biomechanics (Bristol, Avon)2020
The tribology of cartilage: Mechanisms, experimental techniques, and relevance to translational tissue engineering.
Review in Clinical biomechanics (Bristol, Avon), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 64 citations in OpenAlex.
- Next-Generation Cartilage Repair: Clinical Use of Wharton's Jelly MSCs and the Emerging Role of AI-Assisted Bioprinting.Bioengineering (Basel, Switzerland) · 2026Review
- Anisotropic wear behavior of meniscus: Influence of cross-shear and loading magnitude.Journal of the mechanical behavior of biomedical materials · 2026Article
- Toward Cartilage-Mimicking Biomaterials: Biotribological, Biochemical and Structural Evaluation of pHEMA and PVA-Based Hydrogels.ACS omega · 2025Article
- Surface Inspection and Description in Metrology and Tribology-Vol. 2.Materials (Basel, Switzerland) · 2025Article
- Sustained release of exogeneous fetuin-A from Hyaluronic acid microplates decreases joint degeneration, synovial hyperplasia and muscle damage in a murine post-traumatic osteoarthritis model.Arthritis research & therapy · 2025Article
- Review
- Friction of osteoarthritic cartilage with patient-specific synovial fluid: Effect of different loading conditions.Osteoarthritis and cartilage open · 2025Article
- Multi-Scale Analysis of Knee Joint Acoustic Signals for Cartilage Degeneration Assessment.Sensors (Basel, Switzerland) · 2025Article
- Proof-of-concept study of the TriBot: a robot-based test setup for biotribological analyses of curved articular surfaces.Frontiers in bioengineering and biotechnology · 2025Article
- Cartilage Integrity: A Review of Mechanical and Frictional Properties and Repair Approaches in Osteoarthritis.Healthcare (Basel, Switzerland) · 2024Review
- Tribomechanical Properties of PVA/NomexGels (Basel, Switzerland) · 2024Article
- Mechanical Evaluation of Commercially Available Fibrin Sealants for Cartilage Repair.Cartilage · 2024Article
- Elbow dimensions in quadrupedal mammals driven by lubrication regime.Scientific reports · 2024Article
- Impact of hyaluronic acid injection on the knee joint friction.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Article
- Biomimetic Approaches for the Design and Fabrication of Bone-to-Soft Tissue Interfaces.ACS biomaterials science & engineering · 2023Review
- Coefficient of Friction and Height Loss: Two Criteria Used to Determine the Mechanical Property and Stability of Regenerated Versus Natural Articular Cartilage.Biomedicines · 2022Article
- Tribological Evaluation of Silica Nanoparticle Enhanced Bilayer Hydrogels as A Candidate for Cartilage Replacement.Polymers · 2022Article
- Navigating regulatory pathways for translation of biologic cartilage repair products.Science translational medicine · 2022Review
- A Tribological Comparison of Facet Joint, Sacroiliac Joint, and Knee Cartilage in the Yucatan Minipig.Cartilage · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Diarthrodial joints, found at the ends of long bones, function to dissipate load and allow for effortless articulation. Essential to these functions are cartilages, soft hydrated tissues such as hyaline articular cartilage and the knee meniscus, as well as lubricating synovial fluid. Maintaining adequate lubrication protects cartilages from wear, but a decrease in this function leads to tissue degeneration and pathologies such as osteoarthritis. To study cartilage physiology, articular cartilage researchers have employed tribology, the study of lubrication and wear between two opposing surfaces, to characterize both native and engineered tissues. The biochemical components of synovial fluid allow it to function as an effective lubricant that exhibits shear-thinning behavior. Although tribological properties are recognized to be essential to native tissue function and a critical characteristic for translational tissue engineering, tribology is vastly understudied when compared to other mechanical properties such as compressive moduli. Further, tribometer configurations and testing modalities vary greatly across laboratories. This review aims to define commonly examined tribological characteristics and discuss the structure-function relationships of biochemical constituents known to contribute to tribological properties in native tissue, address the variations in experimental set-ups by suggesting a move toward standard testing practices, and describe how tissue-engineered cartilages may be augmented to improve their tribological properties.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.