Evidence map›Paper›PMID 31676001›Full record

Trial reportBMC public health2019

Effect and cost of two successive home visits to increase HIV testing coverage: a prospective study in Lesotho, Southern Africa.

Niklaus Daniel Labhardt, Isaac Ringera, Thabo Ishmael Lejone, Alain Amstutz, Thomas Klimkait, Josephine Muhairwe, Tracy Renee Glass

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02692027 (Same Day Community-based ART Initiation Versus Clinic-based Pre-ART Assessment and Counselling for Individuals Newly Tested HIV-positive During Community-based HIV Testing in Rural Lesotho - a Randomized Controlled Trial), which is not on this map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02692027 phase3completednot on this map

Same Day Community-based ART Initiation Versus Clinic-based Pre-ART Assessment and Counselling for Individuals Newly Tested HIV-positive During Community-based HIV Testing in Rural Lesotho - a Randomized Controlled Trial

TypeinterventionalSponsorSwiss Tropical & Public Health InstituteRan2016 to 2018Enrolled276ConditionsHIV InfectionArmsSame-day ART initiation, Standard of care
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Niklaus Daniel LabhardtDepartment of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland. n.labhardt@swisstph.ch.ORCID http://orcid.org/0000-0003-3599-1791
Isaac RingeraSolidarMed, Swiss Organization for Health in Africa, Maseru, Lesotho.
Thabo Ishmael LejoneSolidarMed, Swiss Organization for Health in Africa, Maseru, Lesotho.
Alain AmstutzDepartment of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland.
Thomas KlimkaitUniversity of Basel, Basel, Switzerland.
Josephine MuhairweSolidarMed, Swiss Organization for Health in Africa, Maseru, Lesotho.
Tracy Renee GlassDepartment of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland.

Funding

Stiftung für Infektiologie beider Basel N/ASwiss National Science Foundation 323530_177576Swiss National Science Foundation IZ07Z0_160876/1Swiss National Science Foundation PCEFP3_181355
6 · The paper itself

Abstract

backgroundHome-based HIV testing and counselling (HB-HTC) is frequently used to increase awareness of HIV status in sub-Saharan Africa. Whereas acceptance of HB-HTC is usually high, testing coverage may remain low due to household members being absent during the home visits. This study assessed whether two consecutive visits, one during the week, one on the weekend, increase coverage.

methodsThe study was a predefined nested-study of the CASCADE-trial protocol and conducted in 62 randomly selected villages and 17 urban areas in Butha-Buthe district, Lesotho. HB-HTC teams visited each village/urban area twice: first during a weekday, followed by a weekend visit to catch-up for household members absent during the week. Primary outcome was HTC coverage after first and second visit. Coverage was defined as all individuals who knew their HIV status out of all household members (present and absent).

resultsHB-HTC teams visited 6665 households with 18,286 household members. At first visit, 69.2 and 75.4% of household members were encountered in rural and urban households respectively (p < 0.001) and acceptance for testing was 88.5% in rural and 79.5% in urban areas (p < 0.001), resulting in a coverage of 61.8 and 61.5%, respectively. After catch-up visit, the HTC coverage increased to 71.9% in rural and 69.4% in urban areas. The number of first time testers was higher at the second visit (47% versus 35%, p < 0.001). Direct cost per person tested and per person tested HIV positive were lower during weekdays (10.50 and 335 USD) than during weekends (20 and 1056 USD).

conclusionsA catch-up visit on weekends increased the proportion of persons knowing their HIV status from 62 to 71% and reached more first-time testers. However, cost per person tested during catch-up visits was nearly twice the cost during first visit.

trial registrationNCT02692027 (prospectively registered on February 21, 2016).

Indexed as

House CallsAdultFemaleHealth Services ResearchHIV InfectionsHumansLesothoMaleMass ScreeningProspective StudiesCommunity-based testingCoverageDoor-to-doorHIVHome-basedTesting

Identifiers

PMID31676001
PMCPMC6825349

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.