ArticleBMC public health2019
Factors associated with tuberculosis disease among children who are household contacts of tuberculosis cases in an urban setting in Malaysia.
Article in BMC public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Screening tests for active pulmonary tuberculosis in children.The Cochrane database of systematic reviews · 2021Pooled it
- Development of a clinical algorithm-based scoring system to diagnose smear-negative pulmonary tuberculosis in Sabah, Malaysia using the modified Delphi method.Journal of global health · 2026Article
- The social imaginary in the daily lives of family caregivers during the prevention of childhood tuberculosis in southern Lima, Peru.Revista peruana de medicina experimental y salud publica · 2025Article
- Predictors of pediatric tuberculosis disease in a pastoralist community, Turkana County, Kenya: a case-control study.BMC infectious diseases · 2025Article
- Prevalence and Associated Factors of Children Tuberculosis in Southeast Asia Countries: A Systematic Review.The Malaysian journal of medical sciences : MJMS · 2024Review
- Tuberculosis infection among children under six in contact with smear positive cases: A study in a hyper endemic area of Iran.Journal of clinical tuberculosis and other mycobacterial diseases · 2023Article
- Tuberculosis Treatment Outcome in Patients with TB-HIV Coinfection in Kuala Lumpur, Malaysia.Journal of tropical medicine · 2021Article
- Sex-related differences in smear-positive pulmonary tuberculosis patients in Kuala Lumpur, Malaysia: Prevalence and associated factors.PloS one · 2021Article
- Prevalence of latent tuberculosis among refugee children in Malaysia.ERJ open research · 2020Article
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5 authors.
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Abstract
backgroundWith the rise in prevalence of childhood tuberculosis (TB) globally, contact tracing should be a powerful strategy for early diagnosis and management, especially in children who are household contacts of active TB cases. Here, we aimed to determine the prevalence and factors associated with TB disease in children who are household contacts of TB cases.
methodsWe used a cross-sectional study with data from the Malaysian TB Information System (TBIS) recorded from 1 January 2014 to 31 December 2017. All children aged 0-14 years who were registered in the TBIS with at least one household contact of TB cases were included in the study. Multiple logistic regression analysis was performed to calculate the adjusted odds ratio (adj. OR) and for adjusting the confounding factors.
resultsA total of 2793 children were included in the study. The prevalence of active TB was 1.5% (95% confidence interval [CI]: 1.31, 1.77%). Children aged < 5 years [adj. OR 9.48 (95% CI: 3.41, 26.36) p < 0.001] with positive tuberculin skin test [adj. OR 395.73 (95% CI: 134.17, 1167.13), p < 0.001] and investigation period of > 6 weeks [adj. OR 7.48 (95% CI: 2.88, 19.43), p < 0.001] had significantly higher odds for TB disease.
conclusionsThe prevalence of TB disease in children who were household contacts of TB cases is relatively low. However, contact tracing programmes should not only focus on children aged < 5 years and with positive tuberculin skin test results, but also be empowered to reduce the investigation period.
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