ArticleThe Journal of chemical physics2019
Simple differences in the protein-membrane attachment mechanism have functional consequences for surface mechanics.
Article in The Journal of chemical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Spatial extent of a single lipid's influence on bilayer mechanics.Physical review. E · 2021Article
- A combined molecular/continuum-modeling approach to predict the small-angle neutron scattering of curved membranes.Chemistry and physics of lipids · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
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Abstract
This paper describes two methods for propagating coupled membrane and embedded particle dynamics with ensembles that are valid to second order in the deformation of the membrane. Proteins and functional lipids associate with cellular membranes, and their attachments influence membrane physical and dynamical properties. Therefore, it is necessary to accurately model the coupled dynamics of the membrane and any associated material of interest. We have developed two methods for coupling membrane and particle dynamics that differ in the binding mechanism of the particle to the surface. The "on-surface" mechanism should be used for particles that slide along the membrane; this description leads to an effective reduction in the membrane surface tension. The "in-surface" mechanism treats the particles as tightly bound to the lipidic binding sites; the method avoids double counting lateral entropy of implicitly modeled lipids. We emphasize the differences between these two mechanisms, when it is appropriate to use them, and how the methods differ from previously used dynamic methods.
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Registered trials
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