Evidence map›Paper›PMID 31675786›Full record

ArticleRhode Island medical journal (2013)2019

Cost-Effectiveness of a Statewide Pre-Exposure Prophylaxis Program for Gay, Bisexual, and Other Men Who Have Sex with Men.

William C Goedel, Philip A Chan, Maximilian R F King, Mattia C F Prosperi, Brandon D L Marshall, Omar Galárraga

Abstract read
In one paragraph

Article in Rhode Island medical journal (2013), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Daily Oral HIV Pre-exposure Prophylaxis Among Young Men Who Have Sex With Men in the United States: Cost-saving at Generic Drug Price.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William C GoedelDepartment of Epidemiology, School of Public Health, Brown University, Providence, RI.
Philip A ChanDepartment of Medicine, Warren Alpert Medical School, Brown University, Providence, RI.
Maximilian R F KingDepartment of Epidemiology, School of Public Health, Brown University, Providence, RI.
Mattia C F ProsperiDepartment of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, Fl.
Brandon D L MarshallDepartment of Epidemiology, School of Public Health, Brown University, Providence, RI.
Omar GalárragaDepartment of Health Services, Policy, and Practice, School of Public Health, Brown University, Providence, RI.

Funding

The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Enhancing Population Impact of HIV Pre-Exposure Prophylaxis ImplementationR21MH109360 · NIMH · BROWN UNIVERSITY · PI CHAN, PHILIP ANDREW, MARSHALL, BRANDON DAVID LEWIS · 2016 to 2017
$459k
NIMH NIH HHS R21 MH109360NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

Pre-exposure prophylaxis (PrEP) is an effective tool for preventing HIV infection among men who have sex with men (MSM), but its cost-effectiveness has varied across settings. Using an agent-based model, we projected the cost-effectiveness of a statewide PrEP program for MSM in Rhode Island over the next decade. In the absence of PrEP, the model predicted an average of 830 new HIV infections over ten years. Scaling up the existing PrEP program to cover 15% of MSM with ten or more partners each year could reduce the number of new HIV infections by 33.1% at a cost of $184,234 per quality-adjusted life-year (QALY) gained. Expanded PrEP use among MSM at high risk for HIV infection has the potential to prevent a large number of new HIV infections but the high drug-related costs may limit the cost-effectiveness of this intervention.

Indexed as

Homosexuality, MaleAnti-HIV AgentsChemopreventionCost-Benefit AnalysisHealth Care CostsHIV InfectionsHumansMalePre-Exposure ProphylaxisQuality-Adjusted Life YearsRhode IslandRisk-TakingAnti-HIV Agentsagent-based modelingcost-effectivenessHIV pre-exposure prophylaxismen who have sex with men

Identifiers

PMID31675786
PMCPMC7461153

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.