Evidence map›Paper›PMID 31675390›Full record

Trial reportAnnals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists2020

Bypassing the blues: Insomnia in the depressed post-CABG population.

Lauren A Waterman, Bea Herbeck Belnap, Marie Anne Gebara, Yan Huang, Kaleab Z Abebe, Bruce L Rollman, Jordan F Karp

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauren A Waterman
Bea Herbeck Belnap
Marie Anne Gebara
Yan Huang
Kaleab Z Abebe
Bruce L Rollman
Jordan F KarpWestern Psychiatric Institute and Clinic, Pittsburgh, PA, 15213 USA. E-MAIL: karpjf@upmc.edu

Funding

CLINICAL RESEARCH TRAINING IN LATE-LIFE MOOD DISORDERST32MH019986 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Carmen Andreescu · 1997 to 2026
$6.9M
Treatment of Depression Following Bypass SurgeryR01HL070000 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROLLMAN, BRUCE LAWRENCE · 2003 to 2007
$5.4M
1/3 Buprenorphine for Late-Life Treatment Resistant DepressionR34MH101371 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KARP, JORDAN F · 2014 to 2016
$672k
NHLBI NIH HHS R01 HL070000NIMH NIH HHS R34 MH101371NIMH NIH HHS T32 MH019986
6 · The paper itself

Abstract

background

backgroundRecovery from coronary artery bypass graft (CABG) surgery often is complicated by depression and insomnia, resulting in poorer health-related quality of life and clinical outcomes. We explored the relationships among depression, insomnia, quality of life, and the impact of a collaborative care strategy on reducing insomnia in patients after CABG surgery.

methods

methodsPatients with a Patient Health Questionnaire score ≥10 were randomized to nurse-delivered collaborative care for depression (n = 150) or their physician’s usual care (n = 152). A convenience sample of patients without depression (n = 151) served as the control group. Using the Hamilton Depression Rating Scale sleep questions, we created an “insomnia index.”

results

resultsAt baseline, 63% of participants who were depressed vs 12% of those who were not depressed reported insomnia. Compared with usual care, fewer collaborative care participants reported insomnia at 8 months, and they tended to have a lower insomnia score (insomnia index change score −0.95 and −1.47, respectively; P = .05) with no time-by- randomization interaction, Cohen’s d = 0.22 (95% confidence interval, −0.001 to 0.43). Participants with baseline insomnia reported greater improvements in mental health–related quality of life (Medical Outcomes Survey 36-item Short Form Mental Component Summary score; −3.32, P = .02), but insomnia was not a significant moderator of the effect of collaborative care.

conclusions

conclusionsThis is the first study to examine the long-term impact on insomnia among post-CABG patients treated for depression. Future collaborative care studies could consider including a therapeutic focus for insomnia.

Indexed as

Coronary Artery BypassDepressive DisorderFemaleFollow-Up StudiesHumansMaleMiddle AgedOutcome Assessment, Health CareQuality of LifeSleep Initiation and Maintenance DisordersCABGdepressionInsomniaPHQ-9

Identifiers

PMID31675390
PMCPMC8936436

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.