ArticleAmerican journal of physiology. Heart and circulatory physiology2020
ASIC1a plays a key role in evoking the metabolic component of the exercise pressor reflex in rats.
Article in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 24 citations in OpenAlex.
- A 10-mg dose of amiloride increases time to failure during blood-flow-restricted plantar flexion in healthy adults without influencing blood pressure.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Trial
- Acid-sensing ion channels in the vasculature: emerging roles in systemic and pulmonary circulations.Pflugers Archiv : European journal of physiology · 2026Review
- Pathological Mechanisms of Tendinopathy Pain: From Mechanical Overload to Neuroimmune-Vascular Crosstalk.Pain research & management · 2026Review
- Inhibition and potentiation of the exercise pressor reflex by pharmacological modulation of TRPC6 in male rats.The Journal of physiology · 2025Article
- Lactate and hydrogen ions play a predominant role in evoking the exercise pressor reflex during ischaemic contractions but not during freely perfused contractions.The Journal of physiology · 2025Article
- Blunted pressor response to peripheral sensory afferent nerve stimulation in intracerebroventricular-streptozotocin injected rats.Autonomic neuroscience : basic & clinical · 2025Article
- Muscle afferent ASIC3 upregulation mediates the exacerbated exercise pressor reflex in male rats following hindlimb ischemia-reperfusion.Physiological reports · 2025Article
- Functional knock out of Acid Sensing Ion Channel 3 prevents the exaggerated exercise pressor reflex in rats exercising on a treadmill.Autonomic neuroscience : basic & clinical · 2025Article
- Abnormal cardiovascular control during exercise: Role of insulin resistance in the brain.Autonomic neuroscience : basic & clinical · 2025Review
- Paradoxical potentiation of the exercise pressor reflex by endomorphin 2 in the presence of naloxone.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Functional knockout of the TRPV1 channel has no effect on the exercise pressor reflex in rats.The Journal of physiology · 2023Article
- Characteristics of acid-sensing ion channel currents in male rat muscle dorsal root ganglion neurons following ischemia/reperfusion.Physiological reports · 2023Article
- Acid-sensing ion channel 1a activates IKCa/SKCa channels and contributes to endothelium-dependent dilation.The Journal of general physiology · 2023Article
- ASIC3 plays a protective role in delayed-onset muscle soreness (DOMS) through muscle acid sensation during exercise.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- The role of acid sensing ion channels in the cardiovascular function.Frontiers in physiology · 2023Review
- Exercise Regulates the Lactate Receptor HCAR1 and ERK1/2-PI3K/Akt Pathways to Promote Cerebral Angiogenesis.Iranian journal of public health · 2022Article
- Novel mechanosensory role for acid sensing ion channel subtype 1a in evoking the exercise pressor reflex in rats with heart failure.The Journal of physiology · 2022Article
- Thromboxane APhysiological reports · 2021Article
- Nerve growth factor in muscle afferent neurons of peripheral artery disease and autonomic function.Neural regeneration research · 2021Article
- ASIC1a does not play a role in evoking the metabolic component of the exercise pressor reflex in a rat model of peripheral artery disease.American journal of physiology. Heart and circulatory physiology · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
The role of the acid-sensing ion channel 1a (ASIC1a) in evoking the exercise pressor reflex is unknown, despite the fact that ASIC1a is opened by decreases in pH in the physiological range. This fact prompted us to test the hypothesis that ASIC1a plays an important role in evoking the exercise pressor reflex in decerebrated rats with freely perfused hindlimb muscles. To test this hypothesis, we measured the effect of injecting two ASIC1a blockers into the arterial supply of the triceps surae muscles on the reflex pressor responses to four maneuvers, namely
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.