Evidence map›Paper›PMID 31675203›Full record

ArticleACS chemical biology2019

Dimensionally Enhanced Antibacterial Library Screening.

Navid J Ayon, William G Gutheil

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in ACS chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Biofilm sensitization to breakJournal of medical microbiology · 2026
    Article
  2. Review
  3. Drug Repurposing: An Emerging Strategy inJournal of microbiology and biotechnology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Navid J AyonDivision of Pharmacology and Pharmaceutical Sciences, School of Pharmacy , University of Missouri-Kansas City , 2464 Charlotte Street , Kansas City , Missouri 64108 , United States.ORCID 0000-0001-5546-912X
William G GutheilDivision of Pharmacology and Pharmaceutical Sciences, School of Pharmacy , University of Missouri-Kansas City , 2464 Charlotte Street , Kansas City , Missouri 64108 , United States.ORCID 0000-0001-7491-4591
University of Missouri–Kansas City · US

Funding

VRE Regulation and InhibitionR15GM126502 · NIGMS · UNIVERSITY OF MISSOURI KANSAS CITY · PI GUTHEIL, WILLIAM G · 2018 to 2018
$465k
Multiplexed antibacterial library screeningR21AI121903 · NIAID · UNIVERSITY OF MISSOURI KANSAS CITY · PI GUTHEIL, WILLIAM G · 2016 to 2017
$403k
NIAID NIH HHS R21 AI121903NIGMS NIH HHS R15 GM126502
6 · The paper itself

Abstract

The emergence and spread of antimicrobial resistance is a major public health threat, and there is an urgent need to develop new strategies to address the issue. In this study, the possibility of enhancing a whole cell based antibacterial library screen by increasing the dimensionality of the screening effort is explored using methicillin-resistant

Indexed as

Anti-Bacterial AgentsHumansMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMicrosomes, LiverAnti-Bacterial Agents

Identifiers

PMID31675203
PMCPMC7580057
OpenAlexW2985581200

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.