ArticleJournal of applied clinical medical physics2019
Intrafraction 4D-cone beam CT acquired during volumetric arc radiotherapy delivery: kV parameter optimization and 4D motion accuracy for lung stereotactic body radiotherapy (SBRT) patients.
Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Assessing the technical capability of a room- and a gantry-mounted kV imaging device for intra-fractional fluoroscopy during stereotactic lung radiotherapy at a C-arm linear accelerator.Physics and imaging in radiation oncology · 2026Article
- Impact of post-correction validation scans on intrafraction tumour misalignment in lung stereotactic body radiotherapy.Physics and imaging in radiation oncology · 2025Article
- Continuing Professional Development-Radiation Therapy.Journal of medical radiation sciences · 2025Article
- Advancing the Collaboration Between Imaging and Radiation Oncology.Seminars in radiation oncology · 2024Review
- A review on 4D cone-beam CT (4D-CBCT) in radiation therapy: Technical advances and clinical applications.Medical physics · 2024Review
- Dynamic cone-beam CT reconstruction using spatial and temporal implicit neural representation learning (STINR).Physics in medicine and biology · 2023Article
- Real-time marker-less tumor tracking with TOF PET:Physics in medicine and biology · 2022Article
- On the evaluation of mobile target trajectory between four-dimensional computer tomography and four-dimensional cone-beam computer tomography.Journal of applied clinical medical physics · 2021Article
- Image quality of 4D in-treatment CBCT acquired during lung SBRT using FFF beam: a phantom study.Radiation oncology (London, England) · 2020Article
- Evaluation of Concomitant Imaging Dose in 4D-CBCT Guided Thoracic Radiotherapy.Technology in cancer research & treatmentArticle
- Clinical Implementation and Accuracy Evaluation of a Novel Intrafraction Cone-beam Computed Tomography Technique for Stereotactic Radiosurgery and Radiotherapy.Journal of medical physicsArticle
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6 authors.
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Abstract
purposeElekta XVI 5.0 allows for four-dimensional cone beam computed tomography (4D CBCT) image acquisition during treatment delivery to monitor intrafraction motion. These images can have poorer image quality due to undersampling of kV projections and treatment beam MV scatter effects. We determine if a universal intrafraction preset can be used for stereotactic body radiotherapy (SBRT) lung patients and validate the accuracy of target motion characterized by XVI intrafraction 4D CBCT.
methodsThe most critical parameter within the intrafraction preset is the nominal AcquisitionInterval, which controls kV imaging acquisition frequency. An optimal value was determined by maximizing the kV frame number acquired up to 1000 frames, typical of pretreatment 4D CBCT. CIRS motion phantom intrafraction phase images for 16 SBRT beams were obtained. Mean target position, time-weighted standard deviation, and amplitude for these images as well as target motion for three SBRT lung patients were compared to respective pretreatment 4D CBCTs. Evaluation of intrafraction 4D CBCT reconstruction revealed inclusion of MV only images acquired to remove MV scatter effects. A workaround to remove these images was developed.
resultsAcquisitionInterval of 0.1°/frame was optimal. The number of kV frames acquired was 567-1116 and showed strong linear correlation with beam monitor unit (MUs). Phantom target motion accuracy was excellent with average differences in target position, standard deviation and amplitude range of ≤0.5 mm. Target tracking for SBRT patients also showed good agreement. Evaluation of phase sorting wave forms showed that inclusion of MV only images significantly impacts intrafraction image reconstruction for patients and use of workaround is necessary.
conclusionsA universal intrafraction imaging preset can be used safely for SBRT lung patients. The number of kV projections with MV delivery parameters varies; however images with fewer kV projections still provided accurate target position information. Impact of the reconstruction workaround was significant and is mandated for all 4D CBCT intrafraction imaging performed at our institution.
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