Evidence map›Paper›PMID 31675073›Full record

ArticleInvestigative ophthalmology & visual science2019

Vision Parameters Most Important to Functionality in Glaucoma.

Ahmed F Shakarchi, Aleksandra Mihailovic, Sheila K West, David S Friedman, Pradeep Y Ramulu

Abstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Correlates of Physical Activity among Adults with Sight Loss in High-Income-Countries: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. [Fitness to drive with glaucoma].Die Ophthalmologie · 2023
    Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmed F ShakarchiThe Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, United States.
Aleksandra MihailovicThe Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, United States.
Sheila K WestThe Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, United States.
David S FriedmanDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States.
Pradeep Y RamuluThe Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, United States.

Funding

Optimizing Safety and Functionality in the Visually ImpairedR01EY022976 · NEI · JOHNS HOPKINS UNIVERSITY · PI RAMULU, PRADEEP YAMMANURU · 2013 to 2024
$5.2M
NEI NIH HHS R01 EY022976
6 · The paper itself

Abstract

Purpose: To determine the importance of various vision parameters to functionality in glaucoma. Methods: Vision was measured using seven parameters: visual acuity (VA), contrast sensitivity (CS), integrated visual field (IVF), area under the log CS function (AULCSF), color vision, stereoacuity, and VA with noise (ViN). Likelihood ratio testing (LRT) determined if the full set of visual parameters significantly explained variability in 10 functional outcomes. For outcomes where the visual contribution was significant, dominance analysis determined the relative importance of the various visual parameters. Results: The analysis included 151 glaucoma patients. Mean age was 70 ± 6.8 years, and 47% were men. Significant visual contributions (LRT P < 0.05) were noted for glaucoma quality of life (GQL-15), reading speed, driving cessation, daily steps, and base of support while walking, but not for fear of falling, balance, gait velocity, stride velocity, and stride length while walking (LRT P > 0.05). The most important parameter (and percent contribution) to vision-explained variability were AULCSF for daily steps (45%), IVF for base of support (35%), VA for reading speed (34%), CS for GQL-15 (30%), and VA for driving cessation (26%). Conclusions: Measures of visual ability are important for several aspects of quality of life and functionality. The most important vision parameter for functionality differs depending on the domain studied. Reading and driving were explained by VA and IVF sensitivity. On the other hand, GQL-15 and daily steps were more heavily influenced by CS and AULCSF, which are rarely performed clinically.

Indexed as

AgedAutomobile DrivingColor VisionContrast SensitivityFemaleGlaucomaHumansMaleMiddle AgedQuality of LifeReadingSickness Impact ProfileSurveys and QuestionnairesVision, OcularVisual AcuityVisual Fields

Identifiers

PMID31675073
PMCPMC6827423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.