Evidence map›Paper›PMID 31674996›Full record

ArticleOptics letters2019

High-sensitivity imaging and quantification of intratumoral distributions of gold nanoparticles using a benchtop x-ray fluorescence imaging system.

Nivedh Manohar, Francisco Reynoso, Sandun Jayarathna, Hem Moktan, Md Foiez Ahmed, Parmeswaran Diagaradjane, Sunil Krishnan, Sang Hyun Cho

Open access · greenAbstract read
In one paragraph

Article in Optics letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Monte Carlo Modeling of An Experimental Benchtop L-shell X-ray Fluorescence Imaging/CT System Adopting Two Silicone Drift Detectors.Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment · 2025
    Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nivedh Manohar
Francisco Reynoso
Sandun Jayarathna
Hem Moktan
Md Foiez Ahmed
Parmeswaran Diagaradjane
Sunil Krishnan
Sang Hyun Cho
The University of Texas MD Anderson Cancer Center · US

Funding

Towards in vivo imaging with benchtop x-ray fluorescence computed tomographyR01EB020658 · NIBIB · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CHO, SANG HYUN · 2016 to 2019
$3.0M
Radiation response modulation of tumors using biocongjugated gold nanoparticlesR01CA155446 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CHO, SANG HYUN, KRISHNAN, SUNIL · 2011 to 2015
$1.5M
NCI NIH HHS R01 CA155446NIBIB NIH HHS R01 EB020658
6 · The paper itself

Abstract

A high-sensitivity benchtop x-ray fluorescence (XRF) imaging system, based on a high-power x-ray source and silicon drift detector, has been developed. This system allows gold L-shell XRF-based quantitative imaging of gold nanoparticles (GNPs) at concentrations as low as 0.007  mg/cm

Identifiers

PMID31674996
PMCPMC7041486
OpenAlexW2981748249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.