Evidence map›Paper›PMID 31674809›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2019

Computational quantification of patient-specific changes in ventricular dynamics associated with pulmonary hypertension.

Henrik Finsberg, Ce Xi, Xiaodan Zhao, Ju Le Tan, Martin Genet, Joakim Sundnes, Lik Chuan Lee, Liang Zhong, Samuel T Wall

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Statistical Atlas-Based Surrogate Model of Biventricular Wall Mechanics.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
  4. Guidelines for mechanistic modeling and analysis in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Henrik FinsbergSimula Research Laboratory, Oslo, Norway.ORCID 0000-0003-3766-2393
Ce XiDepartment of Mechanical Engineering, Michigan State University, East Lansing, Michigan.
Xiaodan ZhaoNational Heart Center Singapore, Singapore.
Ju Le TanNational Heart Center Singapore, Singapore.
Martin GenetMechanics Department and Solid Mechanics Laboratory, École Polytechnique/Le Centre national de la recherche scientifique/Paris-Saclay University, Palaiseau, France.
Joakim SundnesSimula Research Laboratory, Oslo, Norway.
Lik Chuan LeeDepartment of Mechanical Engineering, Michigan State University, East Lansing, Michigan.
Liang ZhongNational Heart Center Singapore, Singapore.
Samuel T WallSimula Research Laboratory, Oslo, Norway.
Michigan State University · USNational Heart Centre Singapore · SGUniversity of Oslo · NOÉcole Polytechnique · FRNational University of Singapore · SGSimula Research Laboratory · NO

Funding

Roles of Ischemia and mechanical dyssynchrony in optimizing CRT responsesR01HL134841 · NHLBI · MICHIGAN STATE UNIVERSITY · PI KASSAB, GHASSAN S, LEE, LIK CHUAN · 2017 to 2020
$2.3M
American Heart Association-American Stroke Association 17SDG33370110NHLBI NIH HHS R01 HL134841
6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) causes an increase in the mechanical loading imposed on the right ventricle (RV) that results in progressive changes to its mechanics and function. Here, we quantify the mechanical changes associated with PAH by assimilating clinical data consisting of reconstructed three-dimensional geometry, pressure, and volume waveforms, as well as regional strains measured in patients with PAH (

Indexed as

Models, CardiovascularPatient-Specific ModelingAdultAgedBlood PressureFemaleHeart VentriclesHumansHypertension, PulmonaryMaleMiddle AgedMyocardial Contractioncardiac mechanicscontractilitydata assimilationpatient-specific simulationspulmonary arterial hypertension

Identifiers

PMID31674809
PMCPMC7132315
OpenAlexW2987566289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.