Evidence map›Paper›PMID 31673928›Full record

ArticleJournal of the Association for Research in Otolaryngology : JARO2019

Effect of Middle-Ear Pathology on High-Frequency Ear Canal Reflectance Measurements in the Frequency and Time Domains.

Gabrielle R Merchant, Jonathan H Siegel, Stephen T Neely, John J Rosowski, Hideko H Nakajima

Abstract read
In one paragraph

Article in Journal of the Association for Research in Otolaryngology : JARO, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The Transmission of Sound to the Cochlea in Normal and Pathological Human Middle Ears.Journal of the Association for Research in Otolaryngology : JARO · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabrielle R MerchantSpeech and Hearing Bioscience and Technology, Harvard Division of Medical Sciences (formerly the Harvard-MIT Division of Health Sciences and Technology), Cambridge, MA, USA. Gabrielle.Merchant@boystown.org.ORCID 0000-0001-7251-1879
Jonathan H SiegelNorthwestern University, Evanston, IL, USA.
Stephen T NeelyBoys Town National Research Hospital, Omaha, NE, USA.
John J RosowskiSpeech and Hearing Bioscience and Technology, Harvard Division of Medical Sciences (formerly the Harvard-MIT Division of Health Sciences and Technology), Cambridge, MA, USA.
Hideko H NakajimaSpeech and Hearing Bioscience and Technology, Harvard Division of Medical Sciences (formerly the Harvard-MIT Division of Health Sciences and Technology), Cambridge, MA, USA.

Funding

COCHLEAR MECHANICS, WAVE PROPAGATION, AND COMPRESSIONR01DC008318 · NIDCD · FATHER FLANAGAN'S BOYS' HOME · PI NEELY, STEPHEN T · 2007 to 2024
$5.2M
Middle-ear Mechanics in Normal and Pathological EarsR01DC004798 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI NAKAJIMA, HIDEKO HEIDI · 2001 to 2016
$4.9M
NIDCD NIH HHS R01 DC004798NIDCD NIH HHS R01 DC008318
6 · The paper itself

Abstract

The effects of middle-ear pathology on wideband acoustic immittance and reflectance at frequencies above 6-8 kHz have not been documented, nor has the effect of such pathologies on the time-domain reflectance. We describe an approach that utilizes sound frequencies as high as 20 kHz and quantifies reflectance in both the frequency and time domains. Experiments were performed with fresh normal human temporal bones before and after simulating various middle-ear pathologies, including malleus fixation, stapes fixation, and disarticulation. In addition to experimental data, computational modeling was used to obtain fitted parameter values of middle-ear elements that vary systematically due to the simulated pathologies and thus may have diagnostic implications. Our results demonstrate that the time-domain reflectance, which requires acoustic measurements at high frequencies, varies with middle-ear condition. Furthermore, the extended bandwidth frequency-domain reflectance data was used to estimate parameters in a simple model of the ear canal and middle ear that separates three major conductive pathologies from each other and from the normal state.

Indexed as

Acoustic Impedance TestsAcoustic StimulationComputer SimulationEar CanalEar, MiddleHumansTemporal Boneconductive hearing lossmiddle-ear pathologypower reflectancetime-domain reflectancewideband acoustic immittance

Identifiers

PMID31673928
PMCPMC6889121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.