Evidence map›Paper›PMID 31673919›Full record

ArticleWorld journal of microbiology & biotechnology2019

The actinobacterium Tsukamurella paurometabola has a functionally divergent arylamine N-acetyltransferase (NAT) homolog.

Vasiliki Garefalaki, Evanthia Kontomina, Charalambos Ioannidis, Olga Savvidou, Christina Vagena-Pantoula, Maria-Giusy Papavergi, Ioannis Olbasalis, Dionysios Patriarcheas, Konstantina C Fylaktakidou, Tamás Felföldi and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparative Investigation of 15 Xenobiotic-MetabolizingApplied and environmental microbiology · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Vasiliki GarefalakiDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Evanthia KontominaDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Charalambos IoannidisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Olga SavvidouDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Christina Vagena-PantoulaDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Maria-Giusy PapavergiDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Ioannis OlbasalisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Dionysios PatriarcheasDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Konstantina C FylaktakidouDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Tamás FelföldiDepartment of Microbiology, ELTE Eötvös Loránd University, Budapest, Pázmány Péter sétány 1/C, 1117, Hungary.
Károly MárialigetiDepartment of Microbiology, ELTE Eötvös Loránd University, Budapest, Pázmány Péter sétány 1/C, 1117, Hungary.
Giannoulis FakisDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece.
Sotiria BoukouvalaDepartment of Molecular Biology and Genetics, Democritus University of Thrace, University Campus, Building 10, 68100, Alexandroupolis, Greece. sboukouv@mbg.duth.gr.ORCID http://orcid.org/0000-0002-3162-5375
Democritus University of Thrace · GREötvös Loránd University · HU

Funding

General Secretariat for Research and Technology HUN40State Scholarships Foundation MIS-5000432
6 · The paper itself

Abstract

Actinobacteria in the Tsukamurella genus are aerobic, high-GC, Gram-positive mycolata, considered as opportunistic pathogens and isolated from various environmental sources, including sites contaminated with oil, urban or industrial waste and pesticides. Although studies look into xenobiotic biotransformation by Tsukamurella isolates, the relevant enzymes remain uncharacterized. We investigated the arylamine N-acetyltransferase (NAT) enzyme family, known for its role in the xenobiotic metabolism of prokaryotes and eukaryotes. Xenobiotic sensitivity of Tsukamurella paurometabola type strain DSM 20162

Indexed as

ActinobacteriaAmino Acid SequenceAminophenolsAniline CompoundsArylamine N-AcetyltransferaseBiotransformationCloning, MolecularEnzyme StabilityGene Expression Regulation, BacterialIsoenzymesKineticsModels, MolecularPhylogenyProtein ConformationRecombinant ProteinsSubstrate Specificity2-aminophenol4-anisidineAminophenolsAniline CompoundsArylamine N-AcetyltransferaseIsoenzymesN-acetyltransferase 1Recombinant ProteinsXenobioticsAcylated dichloroaniline derivativesMalonyl-coenzyme AN-acetyltransferaseNAT enzyme familyN-malonyltransferaseTsukamurella paurometabolaXenobiotics

Identifiers

PMID31673919
OpenAlexW2982352424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.