Evidence map›Paper›PMID 31673900›Full record

ReviewJournal of cardiovascular translational research2020

Electrophysiology Translational Considerations in Cardio-Oncology: QT and Beyond.

Mohammed Alomar, Michael G Fradley

Registry-linked trialOpen access · hybridAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of cardiovascular translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02928497 (Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02928497 naterminatednot on this map

Assessment of the WATCHMAN™ Device in Patients Unsuitable for Oral Anticoagulation (ASAP-TOO)

TypeinterventionalSponsorBoston Scientific CorporationRan2017 to 2025Enrolled481ConditionsStrokeArmsWATCHMAN LAAC Device Implant, Single Antiplatelet Therapy or No Therapy (Control)
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Chest Pain in the Cancer Patient.European cardiology · 2022
    Review
  5. Article
  6. Review
  7. Article
  8. Cardiovascular Toxicities of Bruton's Tyrosine Kinase Inhibitors.Current treatment options in oncology · 2020
    Review
  9. Cardio-Oncology in 2020: Prime for Translation.Journal of cardiovascular translational research · 2020
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mohammed AlomarCardio-Oncology Program, Division of Cardiovascular Medicine, University of South Florida Morsani College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, 12902 USF Magnolia Dr., MCB-CPT, Tampa, FL, 33612-9416, USA.
Michael G FradleyCardio-Oncology Program, Division of Cardiovascular Medicine, University of South Florida Morsani College of Medicine and H. Lee Moffitt Cancer Center and Research Institute, 12902 USF Magnolia Dr., MCB-CPT, Tampa, FL, 33612-9416, USA. mfradley@health.usf.edu.ORCID 0000-0001-8352-8975
University of South Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With improved screening and the advent of many novel therapeutics, patients with cancer are living longer and often surviving their disease. Cardiovascular complications have significant impact on both short- and long-term morbidity and mortality in these patients. While a great deal of attention has been paid to cardiomyopathy and heart failure, many other cardiotoxicities can occur, often at higher rates. Arrhythmias are a particularly common cardiovascular complication of cancer therapeutics and can range from benign to life threatening. Moreover, management of these rhythm disturbances can be challenging in cancer patients for various reasons including drug interactions, as well as underlying hematologic and metabolic disturbances. In this review, we describe the most common therapeutics associated with arrhythmias in cancer patients and provide a discussion about the potential basic and translational mechanisms leading to the development of the various rhythm disturbances which may help to guide prevention and treatment decisions. Clinicaltrials.gov Identifier: NCT02928497.

Indexed as

Cancer SurvivorsCardiac ElectrophysiologyMedical OncologyTranslational Research, BiomedicalAction PotentialsAnimalsAntineoplastic AgentsArrhythmias, CardiacCardiotoxicityHeart Conduction SystemHeart RateHumansNeoplasmsPrognosisRisk AssessmentRisk FactorsAntineoplastic AgentsArrhythmiasAtrial fibrillationCardio-oncologyCardiotoxicityQT prolongation

Identifiers

PMID31673900
OpenAlexW2984677218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.