ArticleOral and maxillofacial surgery2019
Volumetric analysis of MRONJ lesions by semiautomatic segmentation of CBCT images.
Article in Oral and maxillofacial surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- CT-Based Lesion Volume as an Independent Predictor of Surgical Recurrence in Medication-Related Osteonecrosis of the Jaw: A Multi-Center Study of 1007 Patients.Journal of clinical medicine · 2026Article
- Evaluation of Mandibular Trabecular Microarchitecture in Stafne Bone Cavity: A Pilot Study.Diagnostics (Basel, Switzerland) · 2026Article
- Deep learning-based automatic segmentation of MRONJ lesions on CBCT images.BMC oral health · 2026Article
- Radiographic Patterns and Clinical Correlates of Medication-Related Osteonecrosis of the Jaw (MRONJ): A Retrospective Analysis.Journal of clinical medicine · 2026Article
- Stage-related changes of bone density and volume in treatment of medication-related osteonecrosis of the jaw.Scientific reports · 2025Article
- Alveolar Bone Segmentation Methods in Assessing the Effectiveness of Periodontal Defect Regeneration Through Machine Learning of CBCT Data: A Systematic Review.International journal of biomedical imaging · 2025Review
- Comparative analysis of volumetric changes between resection volume of oral tongue cancer and post operative volume of radial forearm flaps.Clinical oral investigations · 2024Article
- The Role of Cone Beam Computed Tomography (CBCT) in the Diagnosis and Clinical Management of Medication-Related Osteonecrosis of the Jaw (MRONJ).Diagnostics (Basel, Switzerland) · 2024Review
- A support vector machine-based algorithm to identify bisphosphonate-related osteonecrosis throughout the mandibular bone by using cone beam computerized tomography images.Dento maxillo facial radiology · 2023Article
- A volumetric study of mandibular condyles in orthognathic patients by semiautomatic segmentation.Oral and maxillofacial surgery · 2022Article
- A Comparison of the Clinical and Radiological Extent of Denosumab (XgevaJournal of clinical medicine · 2021Article
- CBCT imaging and histopathological characteristics of osteoradionecrosis and medication-related osteonecrosis of the jaw.Imaging science in dentistry · 2021Article
- Quantitative Segmentation Analysis of the Radiological Changes by Using ITK-SNAP: Risk Assessment of the Severity and Recurrence of Medication-related Osteonecrosis of the Jaw.International journal of medical sciences · 2021Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to evaluate potential differences in volumes of areas of osteolysis caused by medication-related osteonecrosis of the jaw (MRONJ) between the upper and lower jaw. We aim to analyze the clinical relevance of volumetric measurement of osteolytic lesions for surgical planning of MRONJ patients.
methodsSixty-seven patients who were clinically and histopathologically diagnosed with MRONJ were retrospectively included in this study. Cone beam computed tomography (CBCT) images were evaluated according to localization, affected anatomical structures, and volumetric measurement of osteolytic lesions caused by MRONJ in appliance of CBCT datasets by using ITK-SNAP.
resultsThe most frequently affected localization is the mandible, whereas female patients show significantly more often lesions of the maxilla. The cortical bone was predominantly affected. Furthermore, the affection of teeth, sinus floor, inferior alveolar nerve canal, or even a pathological fracture of the mandible are infrequently existing. The volumetric measurements revealed a statistically significant greater absolute osteolysis volume in males.
conclusionsImage analysis and volumetric measurements of osteolytic lesions of MRONJ patients is a helpful tool to further understand the clinical appearance and identify compromised anatomic landmarks. Volumetric analysis aids in pre-surgical planning and visualizes the individual extent of the disease for each patient.
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