ArticleAdvanced biomedical research2019
Genetic Study of Hepatocyte Nuclear Factor 1 Alpha Variants in Development of Early-Onset Diabetes Type 2 and Maturity-Onset Diabetes of the Young 3 in Iran.
Article in Advanced biomedical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Two case reports of maturity-onset diabetes of the young type 3 caused by the hepatocyte nuclear factor 1α gene mutation.Open medicine (Warsaw, Poland) · 2023Article
- Epidemiology, genetic landscape and classification of childhood diabetes mellitus in the State of Qatar.Journal of diabetes investigation · 2021Article
- Molecular diagnosis of maturity onset diabetes of the young in Iranian patients: improving management.Journal of diabetes and metabolic disorders · 2021Article
- Molecular Genetic Study in a Cohort of Iranian Families Suspected to Maturity-Onset Diabetes of the Young, Reveals a Recurrent Mutation and a High-Risk Variant in theAdvanced biomedical research · 2020Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaturity-onset diabetes of the young (MODY) is a clinically and genetically heterogeneous group of diabetes characterized by noninsulin-dependent, autosomal-dominant disorder with strong familial history, early age of onset, and pancreatic beta-cell dysfunction. Mutations in at least 14 different genes are responsible for various MODY subtypes. Heterozygous mutations in the hepatocyte nuclear factor 1 alpha ( MATERIALS AND
methodsPolymerase chain reaction and Sanger sequencing were performed. All the ten exons of the
resultsMODY3 was confirmed in two large families by detecting a mutation (p.G253E) in coding regions of
conclusionIt seems that
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Identifiers
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Registered trials
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