Evidence map›Paper›PMID 31673495›Full record

ArticleToxicology reports2019

A toxicity profile of the Pheroid® technology in rodents.

Janke Kleynhans, Dale Elgar, Thomas Ebenhan, Jan Rijn Zeevaart, Awie Kotzé, Anne Grobler

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Janke KleynhansDST/NWU Preclinical Drug Development Platform, North-West University, Potchefstroom, 2520, South Africa.
Dale ElgarFaculty of Health Sciences, North-West University, Potchefstroom, 2520, South Africa.
Thomas EbenhanNuclear Medicine, University of Pretoria, Pretoria, 0001, South Africa.
Jan Rijn ZeevaartDST/NWU Preclinical Drug Development Platform, North-West University, Potchefstroom, 2520, South Africa.
Awie KotzéFaculty of Health Sciences, North-West University, Potchefstroom, 2520, South Africa.
Anne GroblerDST/NWU Preclinical Drug Development Platform, North-West University, Potchefstroom, 2520, South Africa.
North-West University · ZASouth African Nuclear Energy Corporation (South Africa) · ZAUniversity of Pretoria · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Pheroid® drug delivery system is now on the threshold of progressing into human clinical trials for various patented pharmaceutical applications and a systematic investigation of its toxicological properties

Indexed as

Drug carrier systemGenotoxicityIn vivo toxicityOECD guidelinesOmega-3-acid ethyl esters

Identifiers

PMID31673495
PMCPMC6816226
OpenAlexW2969807376

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.