ArticleJournal of pediatric intensive care2019
Successful Management of Adolescent Bupropion Overdose with Intravenous Lipid Emulsion Therapy.
Article in Journal of pediatric intensive care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 19 citations in OpenAlex.
- Management of Bupropion Toxicity With Intravenous Lipid Emulsion Therapy in a Pediatric Patient: A Case Report.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Combined lipid emulsion and plasma exchange in massive pediatric bupropion overdose: Case Report.Frontiers in toxicology · 2025Article
- Article
- Mechanisms underlying lipid emulsion resuscitation for drug toxicity: a narrative review.Korean journal of anesthesiology · 2023Review
- Seizure and Other Catastrophes due to Bupropion Overdose: Recent Case Report and Review of Published Cases.Innovations in clinical neuroscience · 2023Article
- Treatment of Bupropion Toxicity with Lipid Emulsion.Journal of pediatric intensive care · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bupropion overdose in the pediatric setting poses significant potential for toxicity. We present the case of a 15-year-old female patient presenting with intentional bupropion overdose resulting in generalized tonic-clonic seizures, severe acidosis, vomiting, and tachycardia after ingestion of between 1,650 to 9,000 mg (24-133 mg/kg) of bupropion. The patient was admitted to pediatric intensive care unit (PICU) where toxicity was resolved promptly following administration of intravenous lipid emulsion (ILE) infusion. ILE is a first-line treatment for other forms of toxicity including unintended local anesthetic administration. ILE use is not a first-line treatment in this setting, but this case presents a positive subsequent patient outcome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.