Evidence map›Paper›PMID 31673441›Full record

ReviewJournal of pharmacopuncture2019

Anti-Asthmatic Effects of

Mohammad Reza Khazdair, Akbar Anaeigoudari, Majid Kianmehr

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of pharmacopuncture, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Quorum Quenching ofPathogens (Basel, Switzerland) · 2025
    Article
  4. The Phytochemical Profile of the Petroleum Ether Extract ofInternational journal of molecular sciences · 2024
    Article
  5. Recent Advances in Potential Health Benefits of Quercetin.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  6. Phytochemical Characteristics and Anti-Inflammatory, Immunoregulatory, and Antioxidant Effects ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Review
  7. Review
  8. Frontiers in microbiology · 2022
    Article
  9. Possible therapeutic effects ofPharmaceutical biology · 2021
    Review
  10. Review
  11. Effects ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Review
  12. Possible therapeutic effects ofPharmaceutical biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Mohammad Reza KhazdairTorbat Jam Faculty of Medical Sciences, Torbat Jam, Iran.
Akbar AnaeigoudariDepartment of Physiology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran.
Majid KianmehrEsfarayen Faculty of Medical sciences, Esfarayen, Iran.
Higher Education Complex Engineering Esfarāyen · IRTorbat Heydarieh University of Medical Sciences · IRUniversity of Jiroft · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe medicinal plants are believed to enhance the natural resistance of the body to infections. Some of the main constituents of the plant and derived materials such as, proteins, lectins and polysaccharides have anti-inflammatory effects. Portulaca oleracea (P. oleracea) were used traditionally for dietary, food additive, spice and various medicinal purposes. This review article is focus on the anti-asthmatic effects of P. oleracea and its constituents.

methodsVarious databases, such as the PubMed, Scopus, and Google Scholar, were searched the keywords including "Portulaca oleracea", "Quercetin", "Anti-inflammatory", "Antioxidant", "Cytokines", "Smooth muscle ", and " Relaxant effects " until the end of Jul 2018.

resultsP. oleracea extracts and its constituents increased IFN-γ, IL-2, IFNγ/IL-4 and IL- 10/IL-4 ratio, but decreased secretion of TNF-α, IL-4 and chemokines in both in vitro and in vivo studies. P. oleracea extracts and quercetin also significantly decreased production of NO, stimulated β-adrenoceptor and/or blocking muscarinic receptors in tracheal smooth muscles. Conclusion: P. oleracea extracts and quercetin showed relatively potent anti-asthmatic effects due to decreased production of NO, inflammatory cytokines and chemokines, reduced oxidant while enhanced antioxidant markers, and also showed potent relaxant effects on tracheal smooth muscles via stimulatory on β-adrenoceptor or/and blocking muscarinic receptors.

Indexed as

anti-inflammatory effectsantioxidant effectsPortulaca oleraceaQuercetinrelaxant effectssmooth muscle

Identifiers

PMID31673441
PMCPMC6820471
OpenAlexW2998800034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.