Evidence map›Paper›PMID 31673381›Full record

SynthesisOpen heart

Mobile phone text-messaging interventions aimed to prevent cardiovascular diseases (Text2PreventCVD): systematic review and individual patient data meta-analysis.

Sheikh Mohammed Shariful Islam, Andrew J Farmer, Kirsten Bobrow, Ralph Maddison, Robyn Whittaker, Leila Anne Pfaeffli Dale, Andreas Lechner, Scott Lear, Zubin Eapen, Louis Wilhelmus Niessen and 5 more

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05628337 (Effects of Mobile Text Intervention on Transitions of Care and Outcomes After Hospitalization With Acute Coronary Syndrome - The TEACH), which is not on this map. Cited by 49 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05628337 naactive not recruitingnot on this map

Effects of Mobile Text Intervention on Transitions of Care and Outcomes After Hospitalization With Acute Coronary Syndrome - The TEACH (Texting After ACS Discharge) Pilot Randomized Trial

TypeinterventionalSponsorSunnybrook Health Sciences CentreRan2022 to 2025Enrolled241ConditionsCoronary Artery DiseaseArmsMotivational texting, Control
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sheikh Mohammed Shariful IslamInstitute for Physical Activity and Nutrition, Deakin University, Geelong, Victoria, Australia.ORCID 0000-0001-7926-9368
Andrew J FarmerNuffield Department of Primary Care Health Science, University of Oxford, Oxford, United Kingdom.
Kirsten BobrowNuffield Department of Primary Care Health Science, University of Oxford, Oxford, United Kingdom.
Ralph MaddisonInstitute for Physical Activity and Nutrition, Deakin University, Geelong, Victoria, Australia.
Robyn WhittakerNational Institute for Health Innovation, The University of Auckland, Auckland, New Zealand.
Leila Anne Pfaeffli DaleNational Institute for Health Innovation, The University of Auckland, Auckland, New Zealand.
Andreas LechnerMedizinische Klinik und Poliklinik IV, Ludwig-Maximillian Universität, Munich, Germany.
Scott LearSt. Paul's Hospital, Vancouver, British Columbia, Canada.
Zubin EapenDepartment of Medicine, Duke University, Durham, North California, United States.
Louis Wilhelmus NiessenFaculty of International Public Health and Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Karla SantoCardiovascular Division, The George Institute for Global Health, Sydney, New South Wales, Australia.ORCID 0000-0001-9047-8865
Sandrine StepienCardiovascular Division, The George Institute for Global Health, Sydney, New South Wales, Australia.
Julie RedfernCardiovascular Division, The George Institute for Global Health, Sydney, New South Wales, Australia.
Anthony RodgersProfessorial Unit, The George Institute for Global Health, Newtown, New South Wales, Australia.
Clara K ChowCardiovascular Division, The George Institute for Global Health, Sydney, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A variety of small mobile phone text-messaging interventions have indicated improvement in risk factors for cardiovascular disease (CVD). Yet the extent of this improvement and whether it impacts multiple risk factors together is uncertain. We aimed to conduct a systematic review and individual patient data (IPD) meta-analysis to investigate the effects of text-messaging interventions for CVD prevention. Methods: Electronic databases were searched to identify trials investigating a text-messaging intervention focusing on CVD prevention with the potential to modify at least two CVD risk factors in adults. The main outcome was blood pressure (BP). We conducted standard and IPD meta-analysis on pooled data. We accounted for clustering of patients within studies and the primary analysis used random-effects models. Sensitivity and subgroup analyses were performed. Results: Nine trials were included in the systematic review involving 3779 participants and 5 (n=2612) contributed data to the IPD meta-analysis. Standard meta-analysis showed that the weighted mean differences are as follows: systolic blood pressure (SBP), -4.13 mm Hg (95% CI -11.07 to 2.81, p<0.0001); diastolic blood pressure (DBP), -1.11 mm Hg (-1.91 to -0.31, p=0.002); and body mass index (BMI), -0.32 (-0.49 to -0.16, p=0.000). In the IPD meta-analysis, the mean difference are as follows: SBP, -1.3 mm Hg (-5.4 to 2.7, p=0.5236); DBP, -0.8 mm Hg (-2.5 to 1.0, p=0.3912); and BMI, -0.2 (-0.8 to 0.4, p=0.5200) in the random-effects model. The impact on other risk factors is described, but there were insufficient data to conduct meta-analyses. Conclusion: Mobile phone text-messaging interventions have modest impacts on BP and BMI. Simultaneous but small impacts on multiple risk factors are likely to be clinically relevant and improve outcome, but there are currently insufficient data in pooled analyses to examine the extent to which simultaneous reduction in multiple risk factors occurs. PROSPERO registration number: CRD42016033236.

Indexed as

cardiovascular diseasescardiovascular risk factorsdiabetesmHealthmobile phonesshort message service

Identifiers

PMID31673381
PMCPMC6802999

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.