Evidence map›Paper›PMID 31673355›Full record

ArticleAntimicrobial resistance and infection control2019

Clinical, microbiological, and molecular epidemiological characteristics of

Siqin Zhang, Xiucai Zhang, Qing Wu, Xiangkuo Zheng, Guofeng Dong, Renchi Fang, Yizhi Zhang, Jianming Cao, Tieli Zhou

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Thymol and carvacrol againstFrontiers in pharmacology · 2024
    Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. <p>Molecular medicine reports · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Integrative genomic and clinical analysis of carbapenem-resistant and susceptibleFrontiers in cellular and infection microbiology · 2026
    Article
  14. Epidemiological features of hypermucoviscousFrontiers in cellular and infection microbiology · 2026
    Article
  15. Glycoconjugate Vaccines Against Nosocomial Klebsiella pneumoniae Infections.Advances in experimental medicine and biology · 2026
    Article
  16. Co-evolution of resistance and virulence inFrontiers in cellular and infection microbiology · 2026
    Review
  17. Article
  18. Article
  19. Article
  20. Genomic Characterization of a Rare K30-ST198 HypervirulentInternational journal of molecular sciences · 2025
    Article

25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siqin Zhang1Department of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000 China.
Xiucai Zhang1Department of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000 China.
Qing Wu1Department of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000 China.
Xiangkuo Zheng2School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, 325000 China.
Guofeng Dong2School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, 325000 China.
Renchi Fang1Department of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000 China.
Yizhi Zhang1Department of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000 China.
Jianming Cao2School of Laboratory Medicine and Life Science, Wenzhou Medical University, Wenzhou, 325000 China.
Tieli Zhou1Department of Clinical Laboratory, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000 China.ORCID 0000-0002-2171-4710

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: The KP-PLA cases from a tertiary teaching hospital in China from January 2016 to December 2017 were systemically studied and elucidated comprehensively. The virulence factors, resistant spectrum, and clones of Results: A total of 163 KP-PLA cases were enrolled, in which the majority of those cases were senior males, and often associated with multiple underlying diseases, including diabetes (49.7%). The remaining cases belonged to healthy individuals (50.3%). The clinical symptoms were common but nonspecific, characterized by increased inflammatory parameters and abnormal liver function parameters. The abscess was often right-sided solitary presentation (58.3%). Cephalosporin or carbapenem plus metronidazole combined with percutaneous puncture or catheter drainage were favorable therapeutics. Although low resistance rates of commonly used antimicrobial drugs (< 10%) were observed, twelve strains were identified as multidrug resistant (MDR) strains, and were mainly isolated from the OHD patients. The hypermucoviscosity, as well as K1 and K2 serotypes accounted for 30.7, 40.5, and 19.0%, respectively. Except for Conclusions: The present study reported the abundant hvKp strains in KP-PLA, as well as convergence of hypervirulent and MDR

Indexed as

AdultAgedChinaFemaleHumansKlebsiella InfectionsKlebsiella pneumoniaeLiver Abscess, PyogenicMaleMiddle AgedMolecular EpidemiologyMultilocus Sequence TypingRetrospective StudiesVirulenceVirulence FactorsVirulence FactorsClinical characteristicsHypervirulent K. pneumoniaeMultidrug resistantPyogenic liver abscessSequence typeVirulence factors

Identifiers

PMID31673355
PMCPMC6819602

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.