ArticleChemical science2019
Electrochemical oxidation induced selective tyrosine bioconjugation for the modification of biomolecules.
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The trial behind it
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Who cites it
35 citing papers in PubMed.
- Cyclopropanol can function as a caged dual-functional warhead for selective electrochemical bioconjugation.Nature chemistry · 2026Article
- Recent Advances in Photocatalyst-Driven Protein Labeling and Proximity Mapping.Chemical record (New York, N.Y.) · 2026Review
- Advances in electrochemical peptide synthesis and modification.Nature reviews. Chemistry · 2026Review
- Mechanochemical Dehydrogenative Phenochalcogenazination: A Pronounced Water Effect.ChemSusChem · 2026Article
- Article
- Electro-induced C-H/S-H cross-coupling for the functionalization/macrocyclization of cysteine-containing peptides.Nature communications · 2025Article
- Catalysis in Chemical Modification of Proteins.ChemCatChem · 2025Article
- Bioorthogonal Reaction of o-Quinone with Furan-2(3H)-One for Site-Selective Tyrosine Conjugation and Construction of Bispecific Antibody Complexes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Electrochemical-induced phosphorylation of arenols and tyrosine containing oligopeptides.iScience · 2024Article
- Amination of Phenols and Halophenols via Pyridinium-Iridium Dual Photocatalysis.ACS catalysis · 2024Article
- Electrochemical synthesis of peptide aldehydes via C‒N bond cleavage of cyclic amines.Nature communications · 2024Article
- Electrochemical labelling of hydroxyindoles with chemoselectivity for site-specific protein bioconjugation.Nature chemistry · 2024Article
- Site-Selective Tyrosine Reaction for Antibody-Cell Conjugation and Targeted Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- A review of recent advances in electrochemical and photoelectrochemical late-stage functionalization classified by anodic oxidation, cathodic reduction, and paired electrolysis.Beilstein journal of organic chemistry · 2024Review
- Electrochemistry in sensing of molecular interactions of proteins and their behavior in an electric field.Mikrochimica acta · 2023Review
- Electrochemical Late-Stage Functionalization.Chemical reviews · 2023Review
- An electroaffinity labelling platform for chemoproteomic-based target identification.Nature chemistry · 2023Article
- Recent developments in the cleavage, functionalization, and conjugation of proteins and peptides at tyrosine residues.Chemical science · 2023Review
- Site-Selective C-H Amination of Phenol-Containing Biomolecules.Organic letters · 2023Article
- Tunable Electrochemical Peptide Modifications: Unlocking New Levels of Orthogonality for Side-Chain Functionalization.Angewandte Chemie (International ed. in English) · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Directly introducing a beneficial functional group into biomolecules under mild, clean and easy-to-handle conditions is of great importance in the field of chemical biology and pharmacology. Herein, we described an electrochemical strategy to perform the bioconjugation of tyrosine residues with phenothiazine derivatives in a rapid and simple manner. In this electrochemical system, various polypeptides and proteins were successfully labelled with excellent site- and chemo-selectivity, and metals, oxidants or additives were also avoided.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.