Evidence map›Paper›PMID 31673311›Full record

ArticleMedChemComm2019

Synthesis of bicyclic 1,4-thiazepines as novel anti-

Franco Vairoletti, Andrea Medeiros, Pablo Fontán, Jennifer Meléndrez, Carlos Tabárez, Gustavo Salinas, Jaime Franco, Marcelo A Comini, Jenny Saldaña, Vojtech Jancik and 2 more

Abstract read
In one paragraph

Article in MedChemComm, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Franco VairolettiLaboratorio de Química Farmacéutica , Departamento de Química Orgánica , Facultad de Química , Universidad de la República , Montevideo , Uruguay . Email: gmahler@fq.edu.uy ; Email: csaiz@fq.edu.uy.ORCID 0000-0002-5160-2250
Andrea MedeirosGroup Redox Biology of Trypanosomes , Institut Pasteur de Montevideo , Montevideo , Uruguay.
Pablo FontánLaboratorio de Química Farmacéutica , Departamento de Química Orgánica , Facultad de Química , Universidad de la República , Montevideo , Uruguay . Email: gmahler@fq.edu.uy ; Email: csaiz@fq.edu.uy.
Jennifer MeléndrezLaboratorio de Química Farmacéutica , Departamento de Química Orgánica , Facultad de Química , Universidad de la República , Montevideo , Uruguay . Email: gmahler@fq.edu.uy ; Email: csaiz@fq.edu.uy.
Carlos TabárezLaboratorio de Química Farmacéutica , Departamento de Química Orgánica , Facultad de Química , Universidad de la República , Montevideo , Uruguay . Email: gmahler@fq.edu.uy ; Email: csaiz@fq.edu.uy.
Gustavo SalinasWorm Biology Laboratory , Unidad Mixta Institut Pasteur de Montevideo-Facultad de Química , UdelaR , Montevideo , Uruguay.ORCID 0000-0003-3350-3002
Jaime FrancoGroup Redox Biology of Trypanosomes , Institut Pasteur de Montevideo , Montevideo , Uruguay.
Marcelo A CominiGroup Redox Biology of Trypanosomes , Institut Pasteur de Montevideo , Montevideo , Uruguay.ORCID 0000-0001-5000-1333
Jenny SaldañaLaboratorio de Experimentación Animal , Depto de Ciencias Farmacéuticas , Facultad de Química , Universidad de la República , Montevideo , Uruguay.
Vojtech JancikCentro Conjunto de Investigación en Química Sustentable UAEM-UNAM , Toluca , Mexico.ORCID 0000-0002-1007-1764
Graciela MahlerLaboratorio de Química Farmacéutica , Departamento de Química Orgánica , Facultad de Química , Universidad de la República , Montevideo , Uruguay . Email: gmahler@fq.edu.uy ; Email: csaiz@fq.edu.uy.ORCID 0000-0003-0612-0516
Cecilia SaizLaboratorio de Química Farmacéutica , Departamento de Química Orgánica , Facultad de Química , Universidad de la República , Montevideo , Uruguay . Email: gmahler@fq.edu.uy ; Email: csaiz@fq.edu.uy.ORCID 0000-0002-6451-1366

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

1,4-Thiazepines derivatives are pharmacologically important heterocycles with different applications in medicinal chemistry. In the present work, we describe the preparation of new bicyclic thiazolidinyl-1,4-thiazepines

Identifiers

PMID31673311
PMCPMC6786244

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.