Evidence map›Paper›PMID 31673263›Full record

ArticleIranian journal of parasitology

Effect of Metabolite Extract of

Loeki Enggar Fitri, Annisa Alkarimah, Alfian Wika Cahyono, Wahyudha Ngatiril Lady, Agustina Tri Endharti, Rivo Yudhinata Brian Nugraha

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Fractions 14 and 36K of Metabolite ExtractInfection and drug resistance · 2023
    Article
  2. Malaria diagnostic update: From conventional to advanced method.Journal of clinical laboratory analysis · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Loeki Enggar FitriDepartment of Parasitology, Malaria Research Group, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Annisa AlkarimahMaster Program in Biomedical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Alfian Wika CahyonoMaster Program in Biomedical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Wahyudha Ngatiril LadyLabarotory of Biomedic, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Agustina Tri EndhartiDepartment of Parasitology, Malaria Research Group, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Rivo Yudhinata Brian NugrahaDepartment of Parasitology, Malaria Research Group, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria eradication has been complicated by the repeated emergence of antimalarial drug resistances. We aimed to determine whether a metabolite extract of

methods

resultsThe metabolite extract affected the morphology of almost all of parasite asexual stages. Schizonts and trophozoites failed to grow and appeared damaged with pycnotic cores and loss of cytoplasmic content. At 8 hours there was a significant decrease in DNA parasite density in culture exposed to 2.6 mg/ml and 13 mg/ml (

conclusionMetabolite extract of

Indexed as

DNA parasite densityPlasmodium falciparum 3D7Streptomyces hygroscopicus subsp hygroscopicus

Identifiers

PMID31673263
PMCPMC6815862

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.