Evidence map›Paper›PMID 31673091›Full record

ArticleScientific reports2019

Reflux finding score is associated with gastroesophageal flap valve status in patients with laryngopharyngeal reflux disease: a retrospective study.

Wei Wu, Lianyong Li, Changmin Qu, Min Wang, Shuwen Liang, Xiaopei Gao, Xinwei Bao, Lei Wang, Hongdan Liu, Haolun Han and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wei WuDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China.
Lianyong LiState Environmental Protection Key Laboratory of Environmental Sense Organ Stress and Health, Beijing, China.ORCID http://orcid.org/0000-0002-0852-7005
Changmin QuState Environmental Protection Key Laboratory of Environmental Sense Organ Stress and Health, Beijing, China.
Min WangDepartment of Gastroenterology, Chinese People Liberation Army 306th Hospital, Beijing, China.
Shuwen LiangDepartment of Gastroenterology, Chinese People Liberation Army 306th Hospital, Beijing, China.
Xiaopei GaoDepartment of Gastroenterology, Chinese People Liberation Army 306th Hospital, Beijing, China.
Xinwei BaoDepartment of Gastroenterology, Chinese People Liberation Army 306th Hospital, Beijing, China.
Lei WangDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China.
Hongdan LiuDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China.
Haolun HanDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China.
Bingxin XuDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China.
Ying ZhouDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China.
Baowei LiDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China.
Yiyan ZhangDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China.
Gang WangDepartment of Otorhinolaryngology Head and Neck Surgery, Chinese People Liberation Army 306th Hospital, Beijing, China. wanggang306yy@126.com.
Changqing ZhongDepartment of Gastroenterology, Chinese People Liberation Army 306th Hospital, Beijing, China. zcq123456789@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic grading of gastroesophageal flap valve (GEFV) is simple and reproducible and offers useful information for reflux activity. To investigate the potential correlation between GEFV grading and reflux finding score (RFS) in patients with laryngopharyngeal reflux disease (LPRD), 225 consecutive Patients with suspected LPRD who underwent both routine upper gastrointestinal endoscopy and laryngoscope were enrolled in our study. Patients with a RFS of more than 7 were diagnosed with LPRD. The GEFV was graded as I through IV according to Hill's classification and was classified into two groups: normal GEFV group (grades I and II) and the abnormal GEFV group (grades III and IV). The percent of GEFV grades I to IV was 39.1%, 39.1%, 12.4%, and 9.3%, respectively. Age was significantly related to an abnormal GEFV (p = 0.002). Gender, BMI, smoke and alcohol were not related to GEFV grade. Fifty-one patients (22.67%) had positive RFS. Reflux finding scores were higher in GEFV grades III and IV than I and II (p < 0.05). Endoscopic grading of GEFV is well correlated with reflux finding score in patients with LPRD. This is a simple and useful technique that provides valuable diagnostic information of LPRD.

Indexed as

AdultAgedAlcohol DrinkingEndoscopy, Digestive SystemEsophagogastric JunctionEsophagusFemaleHumansLaryngopharyngeal RefluxMaleMiddle AgedRetrospective StudiesSeverity of Illness IndexSmoking

Identifiers

PMID31673091
PMCPMC6823359

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.