ArticleScientific data2019
The Personal Genome Project-UK, an open access resource of human multi-omics data.
Article in Scientific data, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Diversity and Representation in Cardiovascular Research: Evidence Gaps, Emerging Models, and Policy Implications.International journal of environmental research and public health · 2026Review
- Publication, funding, and experimental data in support of Human Reference Atlas construction and usage.Scientific data · 2024Article
- Phenotypic Associations With the HMOX1 GT(n) Repeat in European Populations.American journal of epidemiology · 2024Article
- Blood-Based Epigenetic Age Acceleration and Incident Colorectal Cancer Risk: Findings from a Population-Based Case-Control Study.International journal of molecular sciences · 2024Article
- A pipeline for sample tagging of whole genome bisulfite sequencing data using genotypes of whole genome sequencing.BMC genomics · 2023Article
- Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks.Communications biology · 2023Article
- A guide to multi-omics data collection and integration for translational medicine.Computational and structural biotechnology journal · 2023Review
- Open access-enabled evaluation of epigenetic age acceleration in colorectal cancer and development of a classifier with diagnostic potential.Frontiers in genetics · 2023Article
- Evaluation of Epigenetic Age Acceleration Scores and Their Associations with CVD-Related Phenotypes in a Population Cohort.Biology · 2022Article
- The Relationship between Epigenetic Age and Myocardial Infarction/Acute Coronary Syndrome in a Population-Based Nested Case-Control Study.Journal of personalized medicine · 2022Article
- From Forensics to Clinical Research: Expanding the Variant Calling Pipeline for the Precision ID mtDNA Whole Genome Panel.International journal of molecular sciences · 2021Article
- GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline.Frontiers in genetics · 2020Article
- Artificial Intelligence (AI)-Based Systems Biology Approaches in Multi-Omics Data Analysis of Cancer.Frontiers in oncology · 2020Review
- Making multi-omics data accessible to researchers.Scientific data · 2019Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Integrative analysis of multi-omics data is a powerful approach for gaining functional insights into biological and medical processes. Conducting these multifaceted analyses on human samples is often complicated by the fact that the raw sequencing output is rarely available under open access. The Personal Genome Project UK (PGP-UK) is one of few resources that recruits its participants under open consent and makes the resulting multi-omics data freely and openly available. As part of this resource, we describe the PGP-UK multi-omics reference panel consisting of ten genomic, methylomic and transcriptomic data. Specifically, we outline the data processing, quality control and validation procedures which were implemented to ensure data integrity and exclude sample mix-ups. In addition, we provide a REST API to facilitate the download of the entire PGP-UK dataset. The data are also available from two cloud-based environments, providing platforms for free integrated analysis. In conclusion, the genotype-validated PGP-UK multi-omics human reference panel described here provides a valuable new open access resource for integrated analyses in support of personal and medical genomics.
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Registered trials
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