Evidence map›Paper›PMID 31672483›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2019

Secular trends in cognitive trajectories of diverse older adults.

Jet M J Vonk, Miguel Arce Rentería, Justina F Avila, Nicole Schupf, James M Noble, Richard Mayeux, Adam M Brickman, Jennifer J Manly

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Deriving life-course residential histories in brain bank cohorts: A feasibility study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  5. Promoting diverse perspectives: Addressing health disparities related to Alzheimer's and all dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. The role of cognitive and brain reserve in memory decline and atrophy rate in mid and late-life: The SMART-MR study.Cortex; a journal devoted to the study of the nervous system and behavior · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Demographic Effects on Longitudinal Semantic Processing, Working Memory, and Cognitive Speed.The journals of gerontology. Series B, Psychological sciences and social sciences · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jet M J VonkTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Miguel Arce RenteríaTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Justina F AvilaCenter for Health Policy, University of New Mexico, Albuquerque, NM, USA.
Nicole SchupfTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
James M NobleTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Richard MayeuxTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Adam M BrickmanTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA.
Jennifer J ManlyTaub Institute for Research on Alzheimer's Disease and the Aging Brain, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA. Electronic address: jjm71@cumc.columbia.edu.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
VASCULAR FACTORS AND MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASEP01AG007232 · NIA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI SCHUPF, NICOLE · 1989 to 2008
$21.7M
Epidemiology of Biomarkers of Risk and Progression in LOADR01AG037212 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P, SCHUPF, NICOLE · 2010 to 2015
$10.1M
Genetic Epidemiology of Cerebrovascular Factors in Alzheimer's DiseaseRF1AG054023 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P · 2016 to 2018
$8.9M
NCATS NIH HHS UL1 TR001873NIA NIH HHS P01 AG007232NIA NIH HHS R01 AG037212NIA NIH HHS RF1 AG054023
6 · The paper itself

Abstract

introductionThis study aimed to determine if later birth year influences trajectory of age-related cognitive decline across racial/ethnic groups and to test whether years of school, childhood socioeconomic status, and cardiovascular disease burden explain such secular trends.

methodsWe compared cognitive trajectories of global cognition and subdomains in two successive racially/ethnically and educationally diverse birth cohorts of a prospective cohort study.

resultsLater birth year was associated with higher initial cognitive levels for Whites and Blacks, but not Hispanics. Later birth year was also associated with less rapid rate of decline in all three racial/ethnic groups. More years of education, higher childhood socioeconomic status, and, to a smaller extent, greater cardiovascular disease burden accounted for higher intercepts in the later-born cohort, but did not account for attenuated slope of cognitive decline. DISCUSSION: Later birth year is related to a slower rate of age-related decline in some cognitive domains in some racial/ethnic groups. Our analyses suggest that racial/ethnic and social inequalities are part of the mechanisms driving secular trends in cognitive aging and dementia.

Indexed as

AgedAge FactorsBlack or African AmericanCardiovascular DiseasesCognitive DysfunctionDementiaFemaleHispanic or LatinoHumansMaleNeuropsychological TestsProspective StudiesSocioeconomic FactorsWhite PeopleCognitive agingCohort studiesEducationEthnicityRaceRate of changeSocioeconomic statusTime trend

Identifiers

PMID31672483
PMCPMC6925643

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.