Evidence map›Paper›PMID 31672368›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2020

Home environmental and lifestyle factors associated with asthma, rhinitis and wheeze in children in Beijing, China.

Shaodan Huang, Eric Garshick, Louise B Weschler, Chuan Hong, Jing Li, Linyan Li, Fang Qu, Dewen Gao, Yanmin Zhou, Jan Sundell and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Landscape of Aeroallergen Sensitization in Asia.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Review
  5. Early Origins of Asthma and Allergies: Clues From Studies in China.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Review
  6. Article
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  9. Predictive and prognostic value of leptin status in asthma.NPJ primary care respiratory medicine · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Shaodan HuangDepartment of Building Science, Tsitnghua University, Beijing, 100084, China; Beijing Key Lab of Indoor Air Quality Evaluation and Control, Beijing, 100084, China; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, 02115, USA.
Eric GarshickPulmonary, Allergy, Sleep, and Critical Care Medicine Section, Medical Service, VA Boston Healthcare System, Boston, MA, 02132, USA; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA.
Louise B WeschlerDepartment of Building Science, Tsitnghua University, Beijing, 100084, China; 161 Richdale Road, Colts Neck, NJ, 07722, USA.
Chuan HongDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, 02115, USA.
Jing LiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, 02115, USA. Electronic address: jingli@hsph.harvard.edu.cn.
Linyan LiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, 02115, USA.
Fang QuDepartment of Building Science, Tsitnghua University, Beijing, 100084, China; China Meteorological Administration Training Centre, China Meteorological Administration, Beijing, 100081, China.
Dewen GaoBeijing Key Lab of Indoor Air Quality Evaluation and Control, Beijing, 100084, China.
Yanmin ZhouSchool of Architecture, Tsinghua University, Beijing, 100084, China; Beijing Key Lab of Indoor Air Quality Evaluation and Control, Beijing, 100084, China.
Jan SundellSchool of Environmental Science and Engineering, Tianjin University, Tianjing, 300072, China.
Yinping ZhangDepartment of Building Science, Tsitnghua University, Beijing, 100084, China; Beijing Key Lab of Indoor Air Quality Evaluation and Control, Beijing, 100084, China. Electronic address: zhangyp@mail.tsinghua.edu.cn.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, 02115, USA.
Harvard University · USTsinghua University · CNState Key Laboratory of Building Safety and Built Environment · CNChina Meteorological Administration · CNTianjin University · CNVA Boston Healthcare System · US

Funding

COPD and Response to Traffic Related ParticlesR01ES019853 · NIEHS · HARVARD MEDICAL SCHOOL · PI GARSHICK, ERIC · 2012 to 2016
$3.1M
NIEHS NIH HHS R01 ES019853
6 · The paper itself

Abstract

backgroundThe prevalence of asthma and allergic diseases has increased rapidly in urban China since 2000. There has been limited study of associations between home environmental and lifestyle factors with asthma and symptoms of allergic disease in China.

methodsIn a cross-sectional analysis of 2214 children in Beijing, we applied a two-step hybrid Least Absolute Shrinkage and Selection Operator (LASSO) algorithm to identify environmental and lifestyle-related factors associated with asthma, rhinitis and wheeze from a wide range of candidates. We used group LASSO to select variables, using cross-validation as the criterion. Effect estimates were then calculated using adaptive LASSO. Model performance was assessed using Area Under the Curve (AUC) values.

resultsWe found a number of environmental and lifestyle-related factors significantly associated with asthma, rhinitis or wheeze, which changed the probability of asthma, rhinitis or wheeze from -5.76% (95%CI: -7.74%, -3.79%) to 27.4% (95%CI: 16.6%, 38.3%). The three factors associated with the largest change in probability of asthma were short birth length, carpeted floor and paternal allergy; for rhinitis they were maternal smoking during pregnancy, paternal allergy and living close to industrial area; and for wheeze they were carpeted floor, short birth length and maternal allergy. Other home environmental risk factors identified were living close to a highway, industrial area or river, sharing bedroom, cooking with gas, furry pets, cockroaches, incense, printer/photocopier, TV, damp, and window condensation in winter. Lifestyle-related risk factors were child caretakers other than parents, and age<3 for the day-care. Other risk factors included use of antibiotics, and mother's occupation. Major protective factors for wheeze were living in a rural/suburban region, air conditioner use, and mother's occupation in healthcare.

conclusionsOur findings suggest that changes in lifestyle and indoor environments associated with the urbanization and industrialization of China are associated with asthma, rhinitis, and wheeze in children.

Indexed as

AsthmaBeijingChildChild, PreschoolChinaCookingCross-Sectional StudiesEnvironmental ExposureFemaleHumansHypersensitivityLife StyleMalePregnancyPrevalenceRespiratory SoundsAllergyAsthmaHome environmentLASSOLifestyle

Identifiers

PMID31672368
PMCPMC7050389
OpenAlexW2982230148

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.