ArticleThe Journal of the Acoustical Society of America2019
Contrast-enhanced ultrasound imaging using pulse inversion spectral deconvolution.
Article in The Journal of the Acoustical Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Generalized mathematical framework for contrast-enhanced ultrasound imaging with pulse inversion spectral deconvolution.Ultrasonics · 2023Article
- Evaluation of Nonlinear Contrast Pulse Sequencing for Use in Super-Resolution Ultrasound Imaging.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- Three-dimensional visualization and improved quantification with super-resolution ultrasound imaging - validation framework for analysis of microvascular morphology using a chicken embryo model.Physics in medicine and biology · 2021Article
- 3-D H-Scan Ultrasound Imaging and Use of a Convolutional Neural Network for Scatterer Size Estimation.Ultrasound in medicine & biology · 2020Article
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Authors and funding
3 authors.
Funding
Abstract
A contrast-enhanced ultrasound (CEUS) imaging approach, termed pulse inversion spectral deconvolution (PISD), is introduced. The approach uses two Gaussian-weighted Hermite polynomials to form two inverted pulse sequences. The two inversed pulses are then used to filter ultrasound (US) backscattered data and discrimination of the linear and nonlinear signal components. A research US scanner equipped with a linear array transducer was used for data acquisition. The receive data from all channels are shaped using plane wave imaging beamforming with angular compounding (from one to nine angles). In vitro data was collected with a tissue mimicking flow phantom perfused with an US contrast agent using PISD and traditional nonlinear (NLI) US imaging as comparison. The role of imaging frequency (between 4.5 and 6.25 MHz) and mechanical index (from 0.1 to 0.3) were evaluated. Preliminary in vivo data was collected in the hindlimb of three healthy mice. Preliminary experimental findings indicate that the PISD contrast-to-tissue ratio was improved nearly ten times compared to the NLI US imaging approach. Also, the spatial resolution was improved due to the effect of deconvolution and spatial angular compounding. Overall, PISD is a promising postprocessing technique for real-time CEUS imaging.
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