Evidence map›Paper›PMID 31671599›Full record

ArticleMembranes2019

Antituberculosis Drug Interactions with Membranes: A Biophysical Approach Applied to Bedaquiline.

Marina Pinheiro, Heinz Amenitsch, Salette Reis

Open access · goldAbstract read
In one paragraph

Article in Membranes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Marina PinheiroLAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal. mpinheiro@ff.up.pt.ORCID 0000-0002-6931-1355
Heinz AmenitschInstitute of Inorganic Chemistry, Graz University of Technology, Stremayergasse 6/V, 8010 Graz, Austria. heinz.amenitsch@elettra.eu.ORCID 0000-0002-0788-1336
Salette ReisLAQV, REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal. shreis@ff.up.pt.
Universidade do Porto · PTGraz University of Technology · AT

Funding

FEDER POCI/01/0145/ FEDER/007265, and POCI/01/0145 FEDER/30624Fundação para a Ciência e a Tecnologia PT2020 UID/QUI/50006/2013 - POCI/01/0145/FEDER/007265
6 · The paper itself

Abstract

This work focuses on the interaction of the novel and representative antituberculosis (anti-TB) drug bedaquiline (BDQ) with different membrane models of eukaryotic and prokaryotic cells. The effect of BDQ on eukaryotic cell membrane models was assessed using liposomes, namely, multilamellar vesicles (MLVs) made of 1,2-dimyristoyl-

Indexed as

antibioticliposomesmembrane modelsSAXStuberculosisWAXS

Identifiers

PMID31671599
PMCPMC6918463
OpenAlexW2982375479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.