Evidence map›Paper›PMID 31671580›Full record

ArticleAnimals : an open access journal from MDPI2019

Early Pregnancy Induces Expression of STAT1, OAS1 and CXCL10 in Ovine Spleen.

Yujiao Wang, Xu Han, Leying Zhang, Nan Cao, Lidong Cao, Ling Yang

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Expression of IkappaB Family in the Ovine Liver during Early Pregnancy.Animals : an open access journal from MDPI · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Complement regulation in ovine lymph nodes during early pregnancy.Experimental and therapeutic medicine · 2022
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yujiao WangDepartment of Animal Science, College of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056021, China. wang60302@126.com.
Xu HanDepartment of Animal Science, College of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056021, China. hanxx18832015780@163.com.
Leying ZhangDepartment of Animal Science, College of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056021, China. zhangly056000@126.com.
Nan CaoDepartment of Animal Science, College of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056021, China. m680924250@126.com.
Lidong CaoDepartment of Animal Science, College of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056021, China. dong18832072144@163.com.
Ling YangDepartment of Animal Science, College of Life Sciences and Food Engineering, Hebei University of Engineering, Handan 056021, China. yangling@hebu.edu.cn.ORCID 0000-0003-4385-0024
Hebei University of Engineering · CN

Funding

Science and Technology Project of Hebei Province, China 18236601DScience and Technology Research Project of Higher Education Institutions of Hebei Province, China : ZD2016069 ZD2016069
6 · The paper itself

Abstract

Interferon-tau is a maternal recognition factor in ruminant species, and spleen plays an essential role in regulating innate and adaptive immune responses. However, it is not fully understood that early pregnancy induces expression of interferon stimulated genes (ISGs) in the spleen during early pregnancy in ewes. In this study, spleens were collected from ewes at day 16 of the estrous cycle, and on days 13, 16, and 25 of gestation (n = 6 for each group), and RT-qPCR, western blot and immunohistochemistry analysis were used to detect the expression of signal transducer and activator of transcription 1 (STAT1), 2',5'-oligoadenylate synthetase 1 (OAS1), myxovirusresistance protein 1 (Mx1) and C-X-C motif chemokine 10 (CXCL10). The results revealed that

Indexed as

interferon stimulated genespregnancysheepspleen

Identifiers

PMID31671580
PMCPMC6912697
OpenAlexW2982413547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.