Evidence map›Paper›PMID 31671576›Full record

ArticleInternational journal of environmental research and public health2019

QUICK: Quality and Usability Investigation and Control Kit for Mass Spectrometric Data from Detection of Persistent Organic Pollutants.

Wenjing Guo, Jeffrey Archer, Morgan Moore, Jeffrey Bruce, Michelle McLain, Sina Shojaee, Wen Zou, Linda A Benjamin, Anthony Adeuya, Russell Fairchild and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Software tools, databases and resources in metabolomics: updates from 2018 to 2019.Metabolomics : Official journal of the Metabolomic Society · 2020
    Review
  4. Persistent Organic Pollutants in Food: Contamination Sources, Health Effects and Detection Methods.International journal of environmental research and public health · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wenjing GuoU.S. Food & Drug Administration, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA. Wenjing.guo@fda.hhs.gov.
Jeffrey ArcherU.S. Food & Drug Administration, Arkansas Laboratory, 3900 NCTR Road, Jefferson, AR 72079, USA. Jeffrey.Archer@fda.hhs.gov.
Morgan MooreU.S. Food & Drug Administration, Arkansas Laboratory, 3900 NCTR Road, Jefferson, AR 72079, USA. Morgan.Moore@fda.hhs.gov.
Jeffrey BruceU.S. Food & Drug Administration, Arkansas Laboratory, 3900 NCTR Road, Jefferson, AR 72079, USA. Jeffrey.Bruce@fda.hhs.gov.
Michelle McLainU.S. Food & Drug Administration, Arkansas Laboratory, 3900 NCTR Road, Jefferson, AR 72079, USA. Michelle.McLain@fda.hhs.gov.
Sina ShojaeeU.S. Food & Drug Administration, Arkansas Laboratory, 3900 NCTR Road, Jefferson, AR 72079, USA. Sina.Shojaee@fda.hhs.gov.
Wen ZouU.S. Food & Drug Administration, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA. Wen.Zou@fda.hhs.gov.
Linda A BenjaminU.S. Food & Drug Administration, Center for Veterinary Medicine, 7500 Standish Place, Rockville, MD 20855, USA. Linda.Benjamin@fda.hhs.gov.
Anthony AdeuyaU.S. Food & Drug Administration, Center for Food Safety and Applied Nutrition, 5001 Campus Dr, College Park, MD 20740, USA. Anthony.Adeuya@fda.hhs.gov.
Russell FairchildU.S. Food & Drug Administration, Arkansas Laboratory, 3900 NCTR Road, Jefferson, AR 72079, USA. Russell.Fairchild@fda.hhs.gov.
Huixiao HongU.S. Food & Drug Administration, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, USA. huixiao.hong@fda.hhs.gov.ORCID 0000-0001-8087-3968

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent organic pollutants (POPs) cause a significant public and environmental health concern due to their toxicity, long-range transportability, persistence, and bioaccumulation. The US Food and Drug Administration (FDA) has a program to monitor POPs in human and animal foods at ultra-trace levels, using gas chromatography coupled with mass spectrometry (GC-MS). Stringent quality control procedures are practiced within this program, ensuring the reliability and accuracy of these POP results. Due to the complexity of this program's quality control (QC), the decision-making process for data usability was very time-consuming, upward of three analyst hours for a batch of six extracts. We significantly reduced this time by developing a software kit, written in Python, to evaluate instrument and sample QC, along with data usability. A diverse set of 45 samples were tested using our software, QUICK (Quality and Usability Investigation and Control Kit), that resulted in equivalent results provided by a human reviewer. The software improved the efficiency of the analytical process by reducing the need for user intervention, while simultaneously recognizing a 95% decrease in data reduction time, from 3 hours to 10 minutes.

Indexed as

AnimalsEnvironmental PollutantsGas Chromatography-Mass SpectrometryHumansImage Processing, Computer-AssistedOrganic ChemicalsReproducibility of ResultsTime FactorsEnvironmental PollutantsOrganic Chemicalsdata usabilitygas chromatography–mass spectrometry (GC–MS)persistent organic pollutantsquality control

Identifiers

PMID31671576
PMCPMC6862152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.