ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2019
The Interaction of Oxytocin and Social Support, Loneliness, and Cortisol Level in Major Depression.
Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of mind-body therapies on depression among adolescents: a systematic review and network meta-analysis.Frontiers in public health · 2024Pooled it
- Low Dose Ketamine Preconditions Astrocyte Mitochondria to Achieve Antidepressant Efficacy via Adenosine, Humanin, and Melatonin Upregulation and Efflux.Alpha psychiatry · 2026Article
- Oxytocin varies across the life course in a sex-specific way in a human subsistence population.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Pleiotropic effects of oxytocin receptor polymorphisms: influencing striatocortical connectivity in bipolar disorder.International journal of bipolar disorders · 2025Article
- How factors of the therapeutic alliance interact with oxytocin neurotransmission in psychotherapy.Frontiers in psychiatry · 2025Review
- Endogenous Oxytocin and Depressive Symptoms in Drug Abstainers: The Roles of Perceived Social Support and Drug Abstinence Self-Efficacy.Psychology research and behavior management · 2025Article
- Feasibility of Using Serum, Plasma, and Platelet 5-hydroxytryptamine as Peripheral Biomarker for the Depression Diagnosis and Response Evaluation to Antidepressants: Animal Experimental Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Article
- The Influence of Social Dynamics on Biological Aging and the Health of Historically Marginalized Populations: A Biopsychosocial Model for Health Disparities.International journal of environmental research and public health · 2024Review
- The Association between Default-mode Network Functional Connectivity and Childhood Trauma on the Symptom Load in Male Adults with Methamphetamine Use Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Article
- Converged avenues: depression and Alzheimer's disease- shared pathophysiology and novel therapeutics.Molecular biology reports · 2024Review
- Higher oxytocin concentrations occur in subjects who build affiliative relationships with companion robots.iScience · 2023Article
- By what molecular mechanisms do social determinants impact cardiometabolic risk?Clinical science (London, England : 1979) · 2023Review
- Sex matters: The impact of oxytocin on healthy conditions and psychiatric disorders.Comprehensive psychoneuroendocrinology · 2023Article
- Glucocorticoid Receptor Gene (Alpha psychiatry · 2022Article
- Predicting the Treatment Outcomes of Antidepressants Using a Deep Neural Network of Deep Learning in Drug-Naïve Major Depressive Patients.Journal of personalized medicine · 2022Article
- Multiple Aspects of Inappropriate Action of Renin-Angiotensin, Vasopressin, and Oxytocin Systems in Neuropsychiatric and Neurodegenerative Diseases.Journal of clinical medicine · 2022Review
- Consequences of pandemic-associated social restrictions: Role of social support and the oxytocin system.Psychoneuroendocrinology · 2022Review
- Brain oxytocin: how puzzle stones from animal studies translate into psychiatry.Molecular psychiatry · 2021Review
- Perceived pleasantness of gentle touch in healthy individuals is related to salivary oxytocin response and EEG markers of arousal.Experimental brain research · 2020Article
- The Role of Oxytocin in Cardiovascular Protection.Frontiers in psychology · 2020Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveLoneliness is a specific risk factor for depressive symptoms and suicidal behavior. The present study examined whether the serum oxytocin level would interact with social support and buffers loneliness and hypothalamic-pituitary-adrenal (HPA)-axis activity in drug-naïve patients with major depressive disorder (MDD).
methodsTwenty-six patients with MDD (male:female = 3:23; mean age, 45.54 ± 12.97 years) were recruited. The 17-item Hamilton Depression Rating Scale, UCLA Loneliness Scale and self-reported Measurement of Support Function Questionnaire were administered. Serum oxytocin and cortisol levels were assessed using a commercial immunoassay kits.
resultsIn MDD patients, a negative association was found between degrees of social support and loneliness (β= -0.39,
conclusionLow oxytocin level is a vulnerability factor for the buffering effect of social support for loneliness and aberrant HPA-axis activity in MDD patients.
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