Evidence map›Paper›PMID 31671448›Full record

ArticleThe Journal of infectious diseases2019

Status of the Rollout of the Meningococcal Serogroup A Conjugate Vaccine in African Meningitis Belt Countries in 2018.

Ado Bwaka, André Bita, Clément Lingani, Katya Fernandez, Antoine Durupt, Jason M Mwenda, Richard Mihigo, Mamoudou H Djingarey, Olivier Ronveaux, Marie-Pierre Preziosi

Abstract read
In one paragraph

Article in The Journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  10. Real-world impact and effectiveness of MenACWY-TT.Human vaccines & immunotherapeutics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ado BwakaWorld Health Organization (WHO) Inter-Country Support Team West Africa, Ouagadougou, Burkina Faso.
André BitaWorld Health Organization (WHO) Inter-Country Support Team West Africa, Ouagadougou, Burkina Faso.
Clément LinganiWorld Health Organization (WHO) Inter-Country Support Team West Africa, Ouagadougou, Burkina Faso.
Katya FernandezWHO Infectious Hazard Management, Geneva, Switzerland.
Antoine DuruptWHO Initiative for Vaccine Research, Geneva, Switzerland.
Jason M MwendaWHO Regional Office for Africa, Brazzaville, Congo.
Richard MihigoWHO Regional Office for Africa, Brazzaville, Congo.
Mamoudou H DjingareyWHO Infectious Hazard Management, Regional Office for Africa, Brazzaville, Congo.
Olivier RonveauxWHO Infectious Hazard Management, Geneva, Switzerland.
Marie-Pierre PreziosiWHO Initiative for Vaccine Research, Geneva, Switzerland.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundA novel meningococcal serogroup A conjugate vaccine (MACV [MenAfriVac]) was developed as part of efforts to prevent frequent meningitis outbreaks in the African meningitis belt. The MACV was first used widely and with great success, beginning in December 2010, during initial deployment in Burkina Faso, Mali, and Niger. Since then, MACV rollout has continued in other countries in the meningitis belt through mass preventive campaigns and, more recently, introduction into routine childhood immunization programs associated with extended catch-up vaccinations.

methodsWe reviewed country reports on MACV campaigns and routine immunization data reported to the World Health Organization (WHO) Regional Office for Africa from 2010 to 2018, as well as country plans for MACV introduction into routine immunization programs.

resultsBy the end of 2018, 304 894 726 persons in 22 of 26 meningitis belt countries had received MACV through mass preventive campaigns targeting individuals aged 1-29 years. Eight of these countries have introduced MACV into their national routine immunization programs, including 7 with catch-up vaccinations for birth cohorts born after the initial rollout. The Central African Republic introduced MACV into its routine immunization program immediately after the mass 1- to 29-year-old vaccinations in 2017 so no catch-up was needed.

conclusionsFrom 2010 to 2018, successful rollout of MACV has been recorded in 22 countries through mass preventive campaigns followed by introduction into routine immunization programs in 8 of these countries. Efforts continue to complete MACV introduction in the remaining meningitis belt countries to ensure long-term herd protection.

Indexed as

AfricaDisease OutbreaksFemaleGeography, MedicalHumansImmunization ProgramsImmunization, SecondaryMaleMeningitis, MeningococcalMeningococcal VaccinesNeisseria meningitidis, Serogroup APublic Health SurveillanceVaccinationVaccines, ConjugateMenAfriVacMeningococcal VaccinesVaccines, ConjugateAfrican meningitis beltMenAfriVacmeningococcal serogroup Arollout

Identifiers

PMID31671448
PMCPMC6822965

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.