Evidence map›Paper›PMID 31671256›Full record

ReviewCPT: pharmacometrics & systems pharmacology2019

Open Systems Pharmacology Community-An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences.

Jörg Lippert, Rolf Burghaus, Andrea Edginton, Sebastian Frechen, Mats Karlsson, Andreas Kovar, Thorsten Lehr, Peter Milligan, Valerie Nock, Sergej Ramusovic and 9 more

Abstract readReview
In one paragraph

Review in CPT: pharmacometrics & systems pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Best Practices in Physiologically Based Pharmacokinetic (PBPK) Modeling.CPT: pharmacometrics & systems pharmacology · 2026
    Review
  9. Article
  10. Open Systems Pharmacology Community Conference (OSP-CC) Proceedings 2025.CPT: pharmacometrics & systems pharmacology · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jörg LippertClinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
Rolf BurghausClinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
Andrea EdgintonSchool of Pharmacy, University of Waterloo, Waterloo, Canada.
Sebastian FrechenClinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
Mats KarlssonFaculty of Pharmacy, Uppsala University, Uppsala, Sweden.
Andreas KovarPharmacokinetics, Dynamics and Metabolism, Sanofi-Aventis, Frankfurt, Germany.
Thorsten LehrClinical Pharmacy, Saarland University, Saarbrücken, Germany.
Peter MilliganPharmetheus, Uppsala, Sweden.
Valerie NockBoehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Sergej RamusovicPharmacokinetics, Dynamics and Metabolism, Sanofi-Aventis, Frankfurt, Germany.
Matthew RiggsMetrum Research Group, Tariffville, Connecticut, USA.
Stephan SchalleresqLABS GmbH, Saterland, Germany.
Jan SchlenderClinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
Stephan SchmidtCollege of Pharmacy, University of Florida, Florida, Orlando, USA.
Michaël SevestreDesign2Code Inc, Waterloo, Ontario, Canada.
Erik SjögrenFaculty of Pharmacy, Uppsala University, Uppsala, Sweden.
Juri SolodenkoClinical Pharmacometrics, Bayer AG, Wuppertal, Germany.
Alexander StaabBoehringer Ingelheim Pharma GmbH & Co. KG, Biberach, Germany.
Donato TeutonicoPharmacokinetics, Dynamics and Metabolism, Sanofi-Aventis R&D, Alfortville, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Access to InformationComputer SimulationHumansPharmacology, ClinicalSystems Biology

Identifiers

PMID31671256
PMCPMC6930856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.