Evidence map›Paper›PMID 31671241›Full record

ArticlePlant biotechnology journal2020

The dual benefit of a dominant mutation in Arabidopsis IRON DEFICIENCY TOLERANT1 for iron biofortification and heavy metal phytoremediation.

Reena Sharma, Kuo-Chen Yeh

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Plant biotechnology journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. The bHLH Transcription Factor OsbHLH057 Regulates Iron Homeostasis in Rice.International journal of molecular sciences · 2022
    Article
  4. Review
  5. IRON MAN interacts with BRUTUS to maintain iron homeostasis inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  6. Corrigendum.Plant biotechnology journal · 2021
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Reena SharmaAgricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.
Kuo-Chen YehAgricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.ORCID 0000-0002-3791-3423
National Chung Hsing University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the goals of biofortification is to generate iron-enriched crops to combat growth and developmental defects especially iron (Fe) deficiency anaemia. Fe-fortification of food is challenging because soluble Fe is unstable and insoluble Fe is nonbioavailable. Genetic engineering is an alternative approach for Fe-biofortification, but so far strategies to increase Fe content have only encompassed a few genes with limited success. In this study, we demonstrate that the ethyl methanesulfonate (EMS) mutant, iron deficiency tolerant1 (idt1), can accumulate 4-7 times higher amounts of Fe than the wild type in roots, shoots and seeds, and exhibits the metal tolerance and iron accumulation (Metina) phenotype in Arabidopsis. Fe-regulated protein stability and nuclear localisation of the upstream transcriptional regulator bHLH34 were uncovered. The C to T transition mutation resulting in substitution of alanine to valine at amino acid position 320 of bHLH34 (designated as IDT1

Indexed as

Anemia, Iron-DeficiencyArabidopsisArabidopsis ProteinsMetals, HeavyBiodegradation, EnvironmentalBiofortificationGene Expression Regulation, PlantHumansIronMutationPlant RootsArabidopsis ProteinsIronMetals, HeavyArabidopsisbiofortificationheavy metal stressiron deficiencyNicotiana tabacumphytoremediation

Identifiers

PMID31671241
PMCPMC7152604
OpenAlexW2988568739

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.