Evidence map›Paper›PMID 31671236›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Parallel Homochiral and Anti-Parallel Heterochiral Hydrogen-Bonding Interfaces in Multi-Helical Abiotic Foldamers.

Daniela Mazzier, Soumen De, Barbara Wicher, Victor Maurizot, Ivan Huc

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Discrete Stacked Dimers of Aromatic Oligoamide Helices.Angewandte Chemie (International ed. in English) · 2022
    Article
  6. Article
  7. Review
  8. Aromatic Foldamer Helices as α-Helix Extended Surface Mimetics.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniela MazzierDepartment of Pharmacy and Centre for Integrated Protein Science, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, 81377, Munich, Germany.
Soumen DeCBMN Laboratory, Université de Bordeaux, CNRS, IPB, Institut Européen de Chimie et Biologie, 2 rue Escarpit, 33600, Pessac, France.ORCID 0000-0003-4674-9183
Barbara WicherDepartment of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780, Poznan, Poland.ORCID 0000-0003-2254-2508
Victor MaurizotCBMN Laboratory, Université de Bordeaux, CNRS, IPB, Institut Européen de Chimie et Biologie, 2 rue Escarpit, 33600, Pessac, France.
Ivan HucDepartment of Pharmacy and Centre for Integrated Protein Science, Ludwig-Maximilians-Universität, Butenandtstrasse 5-13, 81377, Munich, Germany.ORCID 0000-0001-7036-9696

Funding

FP7 Ideas: European Research Council ERC-2012-AdG-320892
6 · The paper itself

Abstract

A hydrogen-bonding interface between helical aromatic oligoamide foldamers has been designed to promote the folding of a helix-turn-helix motif with a head-to-tail arrangement of two helices of opposite handedness. This design complements an earlier helix-turn-helix motif with a head-to-head arrangement of two helices of identical handedness interface. The two motifs were shown to have comparable stability and were combined in a unimolecular tetra-helix fold constituting the largest abiotic tertiary structure to date.

Indexed as

foldamershelix bundlesmolecular designstructure elucidationtertiary structures

Identifiers

PMID31671236
PMCPMC7004161

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.