Evidence map›Paper›PMID 31671165›Full record

ArticlePloS one2019

Green synthesis of silver nanoparticles using Solanum mammosum L. (Solanaceae) fruit extract and their larvicidal activity against Aedes aegypti L. (Diptera: Culicidae).

Fernanda Pilaquinga, Bianca Morejón, Danny Ganchala, Jeroni Morey, Neus Piña, Alexis Debut, Marco Neira

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  12. Proteomic Response ofInsects · 2022
    Article
  13. Medicinal Plants ofJournal of tropical medicine · 2022
    Review
  14. Evaluation of the biofilm life cycle betweenFrontiers in cellular and infection microbiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fernanda PilaquingaDepartment of Chemistry, University of the Balearic Islands, Palma de Mallorca, Balearic Islands, Spain.ORCID 0000-0002-0841-6313
Bianca MorejónCenter for Research on Health in Latin America, Department of Exact and Natural Sciences, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.ORCID 0000-0001-5142-8996
Danny GanchalaLaboratory of Nanotechnology, Department of Exact and Natural Sciences, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.ORCID 0000-0002-9386-4822
Jeroni MoreyDepartment of Chemistry, University of the Balearic Islands, Palma de Mallorca, Balearic Islands, Spain.
Neus PiñaDepartment of Chemistry, University of the Balearic Islands, Palma de Mallorca, Balearic Islands, Spain.
Alexis DebutCentro de Nanociencia y Nanotecnología, Universidad de las Fuerzas Armadas ESPE, Sangolquí, Ecuador.ORCID 0000-0002-8269-7619
Marco NeiraCenter for Research on Health in Latin America, Department of Exact and Natural Sciences, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.ORCID 0000-0001-8068-5772

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The family of mosquitoes (Diptera: Culicidae) contains several species of major public health relevance due to their role as vectors of human disease. One of these species, Aedes aegypti, is responsible for the transmission of some of the most important vector-borne viruses affecting humankind, including dengue fever, chikungunya and Zika. Traditionally, control of Ae. aegypti and other arthropod species has relied on the use of a relatively small diversity of chemical insecticides. However, widespread and intensive use of these substances has caused significant adverse environmental effects and has contributed to the appearance of pesticide-resistant populations in an increasing number of locations around the world, thereby dramatically reducing their efficiency. Therefore, it becomes urgent to develop novel alternative tools for vector control. In that context, our study aimed at evaluating the insecticidal activity against Ae. aegypti of aqueous extracts obtained from the fruits of Solanum mammosum L., as well as silver nanoparticles synthesized using aqueous extracts from this plant species (SmAgNPs). To perform the test, third instar Ae. aegypti larvae were exposed to increasing concentrations of plant extract and SmAgNPs for 24 h. Our results suggest that both the aqueous extract and SmAgNPs were toxic to the larvae, with SmAgNPs displaying a much higher level of toxicity than the extract alone, as reflected in their LC50 values (0.06 ppm vs 1631.27 ppm, respectively). These results suggest that both S. mammosum extracts and SmAgNPs exhibit noteworthy larvicidal activity, and should be further explored as potential source of alternative tools in the fight against insect vectors of human disease.

Indexed as

AedesAnimalsChemistry Techniques, SyntheticFruitGreen Chemistry TechnologyInsecticidesLarvaMetal NanoparticlesPlant ExtractsPlant LeavesSilverSolanumWaterInsecticidesPlant ExtractsSilverWater

Identifiers

PMID31671165
PMCPMC6822762

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.