ArticlePLoS neglected tropical diseases2019
Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover.
Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Characterizing the Bat Virome of Vietnam: A Systematic Review of Viral Diversity and Zoonotic Potential.Viruses · 2025Pooled it
- Immunopathological Changes in SARS-CoV-2 Critical and Non-critical Pneumonia Patients: A Systematic Review to Determine the Cause of Co-infection.Frontiers in public health · 2020Pooled it
- Multiplex serological profiling reveals diverse avian and mammalian influenza A virus exposure in swine.iScience · 2026Article
- Zoonotic disease risk perceptions and practices related to livestock production and consumption: a qualitative study among animal rearers and veterinary care providers in Northeast India.BMJ public health · 2026Article
- Bat Viral Shedding: A Review of Seasonal Patterns and Risk Factors.Vector borne and zoonotic diseases (Larchmont, N.Y.) · 2025Review
- Decoding the blueprint of receptor binding by filoviruses through large-scale binding assays and machine learning.Cell host & microbe · 2025Article
- Studying bats using a One Health lens: bridging the gap between bat virology and disease ecology.Journal of virology · 2024Review
- Novel filoviruses: indication of a global threat or cause to reassess our risk perception?Npj viruses · 2024Review
- Molecular insights into the Ebola virus life cycle.Nature microbiology · 2024Review
- Ecological countermeasures to prevent pathogen spillover and subsequent pandemics.Nature communications · 2024Review
- Isolation, characterization, and circulation sphere of a filovirus in fruit bats.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Detection of Filoviruses in Bats in Vietnam.Viruses · 2023Article
- NovelViruses · 2023Article
- Marburg and Ebola Virus Infections Elicit a Complex, Muted Inflammatory State in Bats.Viruses · 2023Article
- Structure of the Ebola virus polymerase complex.Nature · 2022Article
- Serological evidence of a pararubulavirus and a betacoronavirus in the geographically isolated Christmas Island flying-fox (Pteropus natalis).Transboundary and emerging diseases · 2022Article
- Ecological study of cave nectar bats reveals low risk of direct transmission of bat viruses to humans.Zoological research · 2022Article
- Correction: Filovirus-reactive antibodies in humans and bats in Northeast India imply zoonotic spillover.PLoS neglected tropical diseases · 2021Article
- Bats and viruses: a death-defying friendship.Virusdisease · 2021Review
Corrections and comments
- Erratum issued
Authors and funding
12 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bats are reservoirs for several zoonotic pathogens, including filoviruses. Recent work highlights the diversity of bat borne filoviruses in Asia. High risk activities at the bat-human interface pose the threat of zoonotic virus transmission. We present evidence for prior exposure of bat harvesters and two resident fruit bat species to filovirus surface glycoproteins by screening sera in a multiplexed serological assay. Antibodies reactive to two antigenically distinct filoviruses were detected in human sera and to three individual filoviruses in bats in remote Northeast India. Sera obtained from Eonycteris spelaea bats showed similar patterns of cross-reactivity as human samples, suggesting them as the species responsible for the spillover. In contrast, sera from Rousettus leschenaultii bats reacted to two different virus glycoproteins. Our results indicate circulation of several filoviruses in bats and the possibility for filovirus transmission from bats to humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.