Evidence map›Paper›PMID 31670958›Full record

ArticleThe Journal of organic chemistry2020

C1-CBP-vancomycin: Impact of a Vancomycin C-Terminus Trimethylammonium Cation on Pharmacological Properties and Insights into Its Newly Introduced Mechanism of Action.

Zhi-Chen Wu, Nicholas A Isley, Akinori Okano, William J Weiss, Dale L Boger

Open access · greenAbstract read
In one paragraph

Article in The Journal of organic chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Vancomycin-Teixobactin Conjugates.Journal of the American Chemical Society · 2025
    Article
  4. Article
  5. Article
  6. Late-stage diversification of bacterial natural products through biocatalysis.Frontiers in bioengineering and biotechnology · 2024
    Review
  7. Article
  8. Article
  9. Divergent Total Synthesis and Characterization of Maxamycins.Journal of the American Chemical Society · 2023
    Article
  10. Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Antibiotic Susceptibility Testing with Raman Biosensing.Antibiotics (Basel, Switzerland) · 2022
    Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zhi-Chen WuDepartment of Chemistry and Skaggs Institute for Chemical Biology , The Scripps Research Institute , 10550 North Torrey Pines Road , La Jolla , California 92037 , United States.
Nicholas A IsleyDepartment of Chemistry and Skaggs Institute for Chemical Biology , The Scripps Research Institute , 10550 North Torrey Pines Road , La Jolla , California 92037 , United States.
Akinori OkanoDepartment of Chemistry and Skaggs Institute for Chemical Biology , The Scripps Research Institute , 10550 North Torrey Pines Road , La Jolla , California 92037 , United States.
William J WeissUniversity of North Texas System , College of Pharmacy , Fort Worth , Texas 76107 , United States.
Dale L BogerDepartment of Chemistry and Skaggs Institute for Chemical Biology , The Scripps Research Institute , 10550 North Torrey Pines Road , La Jolla , California 92037 , United States.ORCID 0000-0002-3966-3317
Scripps Research Institute · USUniversity of North Texas · US

Funding

LUZOPEPTINS, VANCOMYCIN AND RELATED AGENTSR01CA041101 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI BOGER, DALE L · 1985 to 2024
$9.5M
Access to a Saxitoxin-like Library for Binding Studies of Na Voltage ChannelsF32GM114948 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI ISLEY, NICHOLAS A. · 2016 to 2018
$168k
NCI NIH HHS R01 CA041101NIGMS NIH HHS F32 GM114948
6 · The paper itself

Abstract

C1-CBP-vancomycin (

Indexed as

Methicillin-Resistant Staphylococcus aureusVancomycinAnimalsAnti-Bacterial AgentsCationsHumansMiceMicrobial Sensitivity TestsVancomycin ResistanceAnti-Bacterial AgentsCationsVancomycin

Identifiers

PMID31670958
PMCPMC7007832
OpenAlexW2985953060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.