Evidence map›Paper›PMID 31670782›Full record

ArticleBrain : a journal of neurology2019

ARSA variants in α-synucleinopathies.

Mary B Makarious, Monica Diez-Fairen, Lynne Krohn, Cornelis Blauwendraat, Sara Bandres-Ciga, Jinhui Ding, Lasse Pihlstrøm, Henry Houlden, Sonja W Scholz, Ziv Gan-Or

Abstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain : a journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Association of Rare Variants in ARSA with Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2023
    Pooled it
  2. Article
  3. Article
  4. Association of rare variants inmedRxiv : the preprint server for health sciences · 2023
    Article
  5. Review
  6. Roles of α-Synuclein and Disease-Associated Factors inInternational journal of molecular sciences · 2022
    Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Mary B MakariousNeurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Monica Diez-FairenLaboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Lynne KrohnDepartment of Human Genetics, McGill University, Montréal, Québec, Canada.
Cornelis BlauwendraatLaboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Sara Bandres-CigaLaboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Jinhui DingLaboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Lasse PihlstrømDepartment of Neurology, Oslo University Hospital, Oslo, Norway.
Henry HouldenDepartment of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK.
Sonja W ScholzNeurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
Ziv Gan-OrDepartment of Human Genetics, McGill University, Montréal, Québec, Canada.

Funding

Genetic characterization of atypical parkinsonismZIANS003154 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SCHOLZ, SONJA · 2016 to 2025
$15.4M
Genome wide SNP analysis in Parkinson's diseaseZ01AG000949 · NIA · NATIONAL INSTITUTE ON AGING · PI SINGLETON, ANDREW B · 2006 to 2008
$2.6M
Intramural NIH HHS Z01 AG000949Intramural NIH HHS ZIA NS003154Medical Research Council G0802760Medical Research Council G1001253Medical Research Council G108/638Medical Research Council MR/J004758/1Medical Research Council MR/S01165X/1The Dunhill Medical Trust R605/0717Wellcome Trust 104033
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Parkinson DiseaseSynucleinopathiesalpha-SynucleinCerebroside-SulfataseHumansMolecular Chaperonesalpha-SynucleinCerebroside-SulfataseMolecular Chaperones

Identifiers

PMID31670782
PMCPMC6906592

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.