Evidence map›Paper›PMID 31670432›Full record

ArticleAddiction biology2020

Early life temperamental anxiety is associated with excessive alcohol intake in adolescence: A rhesus monkey (Macaca mulatta) model.

Elizabeth K Wood, Ryno Kruger, Elysha Cash, Stephen G Lindell, Melanie L Schwandt, Christina S Barr, Stephen J Suomi, J Dee Higley

Open access · greenAbstract read
In one paragraph

Article in Addiction biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Resilience to Stress: Lessons from Rodents about Nature versus Nurture.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2022
    Review
  4. Factors Influencing Adolescent Anxiety: The Roles of Mothers, Teachers and Peers.International journal of environmental research and public health · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Elizabeth K WoodDepartment of Psychology, Brigham Young University, Provo, Utah, 84602, USA.ORCID 0000-0001-6407-295X
Ryno KrugerDepartment of Psychology, Brigham Young University, Provo, Utah, 84602, USA.
Elysha CashDepartment of Psychology, Brigham Young University, Provo, Utah, 84602, USA.
Stephen G LindellSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland, 20852, USA.
Melanie L SchwandtLaboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, NIH, Bethesda, Maryland, 20892, USA.
Christina S BarrSection of Comparative Behavioral Genomics, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, Maryland, 20852, USA.
Stephen J SuomiSection of Comparative Ethology, Eunice Shriver Kennedy National Institute of Child Health and Human Development, NIH, Poolesville, Maryland, 20837, USA.
J Dee HigleyDepartment of Psychology, Brigham Young University, Provo, Utah, 84602, USA.
Brigham Young University · USNational Institute on Alcohol Abuse and Alcoholism · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

Early Environments and Genetic Effects on Alcohol Abuse and Associated BehaviorZ01AA000214 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI HEILIG, MARKUS · 2002 to 2008
$2.8M
Stress, HPA Axis Response, Monoamine Functioning and AlcZ01AA000077 · NIAAA · ALCOHOL ABUSE AND ALCOHOLISM · PI HIGLEY, JAMES DEE · 1994 to 2006
–
PSYCHOBIOLOGY OF ANTISOCIAL BEHAVIOR, SOCIAL COMPETENCE, AND PSYCHOSOMATIC HEALTHZ01AA000079 · NIAAA · ALCOHOL ABUSE AND ALCOHOLISM · PI HIGLEY, JAMES DEE · 1994 to 2006
–
NONHUMAN PRIMATE MODELS OF ALCOHOL CONSUMPTION AND EXCESSIVE AGGRESSIONZ01AA000277 · NIAAA · ALCOHOL ABUSE AND ALCOHOLISM · PI HIGLEY, JAMES DEE · 1990 to 2006
–
Intramural NIH HHS Z01 AA000077Intramural NIH HHS Z01 AA000079Intramural NIH HHS Z01 AA000214Intramural NIH HHS Z01 AA000277
6 · The paper itself

Abstract

Teenage alcohol abuse is a major health concern, particularly because the majority of alcohol consumed by teenagers is via binge drinking, a known risk factor for increasing the likelihood for the development of future alcohol use disorders (AUDs). Identifying individuals at risk for excessive alcohol intake in adolescence is a step toward developing effective preventative measures and intervention programs. As adults with AUDs tend to self-medicate their anxiety with alcohol, this longitudinal study assesses the role of infant anxiety-like temperament in the development of adolescent alcohol abuse using a nonhuman primate model. From birth until they were 5 months of age, behaviors of 64 rhesus monkeys (Macaca mulatta) were coded twice a week using an objective mother-infant scoring system that included behaviors traditionally used to assess anxiety and fearfulness in rhesus monkeys. When subjects were four months old, plasma cortisol was obtained. When subjects were adolescents (M

Indexed as

Alcohol DrinkingAlcoholismAnimalsAnxietyDisease Models, AnimalFemaleHydrocortisoneLongitudinal StudiesMacaca mulattaMaleStress, PsychologicalUnderage DrinkingHydrocortisonealcohol abusealcohol use disordersearly anxietyearly riskrhesus monkeystemperament

Identifiers

PMID31670432
PMCPMC9398892
OpenAlexW2983338211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.